ArticleBMC microbiology2009
Staphylococcus epidermidis strains isolated from breast milk of women suffering infectious mastitis: potential virulence traits and resistance to antibiotics.
Article in BMC microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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66 citing papers in PubMed, 139 citations in OpenAlex.
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- The New SH3b_T Domain Increases the Structural and Functional Variability Among SH3b-Like CBDs from Staphylococcal Phage Endolysins.Probiotics and antimicrobial proteins · 2025Article
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- The Role of Targeted Microbiota Therapy in the Prevention and Management of Puerperal Mastitis.Diseases (Basel, Switzerland) · 2025Review
- A new bacteriophage infectingmSphere · 2025Article
- Advances in the Detection and Identification of Bacterial Biofilms Through NIR Spectroscopy.Foods (Basel, Switzerland) · 2025Article
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- Prevalence, Antibiotic Resistance Pattern, and Molecular Characteristics ofJournal of tropical medicine · 2025Article
- Somatic cell count as an indicator of subclinical mastitis and increased inflammatory response in asymptomatic lactating women.Microbiology spectrum · 2024Article
- The Association Between Lactational Infective Mastitis and the Microbiome: Development, Onset, and Treatments.Cureus · 2024Review
- Synergistic removal ofFrontiers in microbiology · 2024Article
- High-Pressure Processing of Human Milk: A Balance between Microbial Inactivation and Bioactive Protein Preservation.The Journal of nutrition · 2023Article
- Interrogating the role of the milk microbiome in mastitis in the multi-omics era.Frontiers in microbiology · 2023Review
- Metagenomic assessment of the bacterial breastfeeding microbiome in mature milk across lactation.Frontiers in pediatrics · 2023Article
- Random amplified polymorphic DNA analysis reveals no clear link between Staphylococcus epidermidis and acute mastitis.The Australian & New Zealand journal of obstetrics & gynaecology · 2022Article
- Interactions between human milk oligosaccharides, microbiota and immune factors in milk of women with and without mastitis.Scientific reports · 2022Article
- Article
- Human milk microbial species are associated with infant head-circumference during early and late lactation in Guatemalan mother-infant dyads.Frontiers in microbiology · 2022Article
- Human milk microbial species are associated with mild growth deficits during early infancy among Guatemalan mother-infant dyads.Frontiers in microbiomes · 2022Article
6 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough Staphylococcus aureus is considered the main etiological agent of infectious mastitis, recent studies have suggested that coagulase-negative staphylococci (CNS) may also play an important role in such infections. The aims of this work were to isolate staphylococci from milk of women with lactational mastitis, to select and characterize the CNS isolates, and to compare such properties with those displayed by CNS strains isolated from milk of healthy women.
resultsThe milk of 30 women was collected and bacterial growth was noted in 27 of them, of which Staphylococcus epidermidis was isolated from 26 patients and S. aureus from 8. Among the 270 staphylococcal isolates recovered from milk of women with mastitis, 200 were identified as Staphylococcus epidermidis by phenotypic assays, species-specific PCR and PCR sequencing. They were typified by pulsed field gel electrophoresis (PFGE) genotyping. The PFGE profiles of the S. epidermidis strains were compared with those of 105 isolates from milk of healthy women. A representative of the 76 different PFGE profiles was selected to study the incidence of virulence factors and antibiotic resistance. The number of strains that contained the biofilm-related icaD gene and that showed resistance to oxacillin, erythromycin, clindamycin and mupirocin was significantly higher among the strains isolated from mastitic milk.
conclusionS. epidermidis may be a frequent but largely underrated cause of infectious mastitis in lactating women. The resistance to diverse antibiotics and a higher ability to form biofilms found among the strains isolated from milk of women suffering mastitis may explain the chronic and/or recurrent nature of this infectious condition.
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