ArticleACS nano2009
Label-free, electrical detection of the SARS virus N-protein with nanowire biosensors utilizing antibody mimics as capture probes.
Article in ACS nano, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it, 222 citations in OpenAlex.
- Updating the use of nano-biosensors as promising devices for the diagnosis of coronavirus family members: A systematic review.Journal of pharmaceutical and biomedical analysis · 2022Pooled it
- Multi-scale computational insights into West Nile virus E-protein adsorption on graphene and phosphorene nanomaterials.Nanoscale advances · 2026Article
- A Review of Readout Circuit Schemes Using Silicon Nanowire Ion-Sensitive Field-Effect Transistors for pH-Sensing Applications.Biosensors · 2025Review
- Nanomaterial-based sensors for microbe detection: a review.Discover nano · 2024Review
- Advances in nanobiosensors during the COVID-19 pandemic and future perspectives for the post-COVID era.Nano convergence · 2024Review
- Photonic-Plasmonic Coupling Enhanced Fluorescence Enabling Digital-Resolution Ultrasensitive Protein Detection.Small (Weinheim an der Bergstrasse, Germany) · 2023Article
- Outlook of various diagnostics and nanodiagnostic techniques for COVID-19.Biosensors & bioelectronics: X · 2022Article
- Nanomaterials-based sensors for the detection of COVID-19: A review.Bioengineering & translational medicine · 2022Review
- Review
- Progress in COVID research and developments during pandemic.View (Beijing, China) · 2022Review
- Utilizing Electrochemical-Based Sensing Approaches for the Detection of SARS-CoV-2 in Clinical Samples: A Review.Biosensors · 2022Review
- Unique Properties of Surface-Functionalized Nanoparticles for Bio-Application: Functionalization Mechanisms and Importance in Application.Nanomaterials (Basel, Switzerland) · 2022Review
- An Insight Into Detection Pathways/Biosensors of Highly Infectious Coronaviruses.Molecular biotechnology · 2022Review
- Rapid diagnosis of COVID-19RSC advances · 2022Review
- Review
- A molecular dynamic study on the ability of phosphorene for designing new sensor for SARS-CoV-2 detection.Journal of molecular liquids · 2022Article
- Current molecular diagnostics assays for SARS-CoV-2 and emerging variants.Methods in microbiology · 2022Article
- Highly sensitive, scalable, and rapid SARS-CoV-2 biosensor based on InNano research · 2022Article
- Nanoagent-based theranostic strategies against human coronaviruses.Nano research · 2022Review
- Point-of-Care Testing-The Key in the Battle against SARS-CoV-2 Pandemic.Micromachines · 2021Review
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Antibody mimic proteins (AMPs) are polypeptides that bind to their target analytes with high affinity and specificity, just like conventional antibodies, but are much smaller in size (2-5 nm, less than 10 kDa). In this report, we describe the first application of AMP in the field of nanobiosensors. In(2)O(3) nanowire based biosensors have been configured with an AMP (Fibronectin, Fn) to detect nucleocapsid (N) protein, a biomarker for severe acute respiratory syndrome (SARS). Using these devices, N protein was detected at subnanomolar concentration in the presence of 44 microM bovine serum albumin as a background. Furthermore, the binding constant of the AMP to Fn was determined from the concentration dependence of the response of our biosensors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.