ArticleInternational journal of nanomedicine2009
Tunable drug loading and release from polypeptide multilayer nanofilms.
Article in International journal of nanomedicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Article
- Protein-based layer-by-layer films for biomedical applications.Chemical science · 2024Review
- Crosslinked Polypeptide Films via RAFT-Mediated Continuous Assembly of Polymers.Angewandte Chemie (International ed. in English) · 2022Article
- Nisin/polyanion layer-by-layer films exhibiting different mechanisms in antimicrobial efficacy.RSC advances · 2020Article
- Capsule-Integrated Polypeptide Multilayer Films for Effective pH-Responsive Multiple Drug Co-Delivery.ACS applied materials & interfaces · 2018Article
- Biomimetic Layer-by-Layer Self-Assembly of Nanofilms, Nanocoatings, and 3D Scaffolds for Tissue Engineering.International journal of molecular sciences · 2018Review
- Layer-by-layer assembled polymeric thin films as prospective drug delivery carriers: design and applications.Biomaterials research · 2018Review
- Electrostatic self-assembly of multilayer copolymeric membranes on the surface of porous tantalum implants for sustained release of doxorubicin.International journal of nanomedicine · 2011Article
- Nanoencapsulating living biological cells using electrostatic layer-by-layer self-assembly: platelets as a model.Journal of materials research · 2011Article
- Ibuprofen-loaded poly(lactic-co-glycolic acid) films for controlled drug release.International journal of nanomedicine · 2011Article
- Polypeptide multilayer film co-delivers oppositely-charged drug molecules in sustained manners.Biomacromolecules · 2010Article
- A stimuli-responsive hydrogel for doxorubicin delivery.Biomaterials · 2010Article
- Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans.Biomacromolecules · 2010Article
- Cefazolin embedded biodegradable polypeptide nanofilms promising for infection prevention: a preliminary study on cell responses.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2010Article
- Electrostatic surface modifications to improve gene delivery.Expert opinion on drug delivery · 2010Review
- Interleukin 12 a key immunoregulatory cytokine in infection applications.International journal of molecular sciences · 2010Review
- Advances in polyelectrolyte multilayer nanofilms as tunable drug delivery systems.Nanotechnology, science and applications · 2009Review
- Multilayer polypeptide nanoscale coatings incorporating IL-12 for the prevention of biomedical device-associated infections.Biomaterials · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polypeptide multilayer nanofilms were prepared using electrostatic layer-by-layer self-assembly nanotechnology. Small charged drug molecules (eg, cefazolin, gentamicin, and methylene blue) were loaded in polypeptide multilayer nanofilms. Their loading and release were found to be pH-dependent and could also be controlled by changing the number of film layers and drug incubation time, and applying heat-treatment after film formation. Antibioticloaded polypeptide multilayer nanofilms showed controllable antibacterial properties against Staphylococcus aureus. The developed biodegradable polypeptide multilayer nanofilms are capable of loading both positively- and negatively-charged drug molecules and promise to serve as drug delivery systems on biomedical devices for preventing biomedical device-associated infection, which is a significant clinical complication for both civilian and military patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.