ArticleNature structural & molecular biology2009
Metabolism control by the circadian clock and vice versa.
Article in Nature structural & molecular biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed.
- Gut microbiota-regulated glutathione metabolic rhythms restore obesity-induced colonic inflammatory oscillations.Gut microbes · 2026Article
- Exposure to Dim Light at Night Impairs Photoperiodic and Metabolic Gene Expression in Syrian Hamsters (Mesocricetus auratus).Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Circadian Syndrome and Stress Urinary Incontinence in Adult American Women: A NHANES Cross-Sectional Study.Urology research & practice · 2026Article
- Ovarian Development in Channa argus var.: Joint Mediation by Melatonin, the cAMP Signaling Pathway, and the PI3K-Akt Signaling Pathway in Response to Photoperiod.Marine biotechnology (New York, N.Y.) · 2026Article
- Article
- Identification of biological rhythm disorder profiles and associated problematic digital behaviors among university students: a latent profile analysis.BMC psychology · 2026Article
- Association between circadian syndrome and gallstones in US adult: a cross-sectional study of NHANES 2017-2020.BMC gastroenterology · 2024Article
- Endogenous clock-mediated regulation of intracellular oxygen dynamics is essential for diazotrophic growth of unicellular cyanobacteria.Nature communications · 2024Article
- Article
- The impact and role of identified long noncoding RNAs in nonalcoholic fatty liver disease: A narrative review.Journal of clinical laboratory analysis · 2023Review
- Endogenous ceramide phosphoethanolamine modulates circadian rhythm via neural-glial coupling inNational science review · 2022Article
- Aldosterone-Regulated Sodium Transport and Blood Pressure.Frontiers in physiology · 2022Review
- Circadian clock control of tRNA synthetases inF1000Research · 2022Article
- Circadian Rhythms, the Gut Microbiome, and Metabolic Disorders.Gastro hep advances · 2022Review
- Bioinformatics and Systems Biology of Circadian Rhythms: BIO_CYCLE and CircadiOmics.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Circadian rhythm disruption with high-fat diet impairs glycemic control and bone quality.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Human circadian variations.The Journal of clinical investigation · 2021Review
- Only time will tell: the interplay between circadian clock and metabolism.Chronobiology international · 2021Review
- Review
- Widely rhythmic transcriptome iniScience · 2021Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Circadian rhythms govern a wide variety of physiological and metabolic functions in most organisms. At the heart of these regulatory pathways in mammals is the clock machinery, a remarkably coordinated transcription-translation system that relies on dynamic changes in chromatin states. Recent findings indicate that regulation also goes the other way, as specific elements of the clock can sense changes in cellular metabolism. Understanding in full detail the intimate links between cellular metabolism and the circadian clock machinery will provide not only crucial insights into system physiology but also new avenues toward pharmacological intervention of metabolic disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.