ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2009
Arterial-cardiac baroreflex function: insights from repeated squat-stand maneuvers.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 59 citations in OpenAlex.
- Breathing technique-dependent acute cardiopulmonary responses during squats in healthy females.Physiological reports · 2026Trial
- Heart rate variability response of intensity-matched strength training dependent on body position in females: a pilot randomized crossover study : Autonomic responses of strength training depending on body position.Scientific reports · 2025Trial
- Orthostatic-dependent cardiopulmonary responses among trained females during intensity matched resistance exercises in a pilot randomized crossover study.Scientific reports · 2025Trial
- Effects of Daylong Exposure to Indoor Overheating on Thermal and Cardiovascular Strain in Older Adults: A Randomized Crossover Trial.Environmental health perspectives · 2024Trial
- The impact of mild hypohydration and sex on the cardiovascular responses to progressive lower-body negative pressure.European journal of applied physiology · 2026Article
- Moderate heart rate-matched hypoxic exercise: autonomic and cardiovascular responses to different degrees of hypoxic stress.European journal of applied physiology · 2026Article
- Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit-stand maneuvers and spontaneous rest.Physiological reports · 2025Article
- Assessment of baroreflex sensitivity during isometric handgrip exercise and oscillatory lower body negative pressure.Journal of Taibah University Medical Sciences · 2023Article
- Hypobaric hypoxia and cardiac baroreflex sensitivity in young women.American journal of physiology. Heart and circulatory physiology · 2022Article
- Influence of high-intensity interval training to exhaustion on the directional sensitivity of the cerebral pressure-flow relationship in young endurance-trained men.Physiological reports · 2022Article
- Sedentary behavior is associated with reduced cardiovagal baroreflex sensitivity in healthy adults.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Does oscillation size matter? Impact of added resistance on the cerebral pressure-flow Relationship in females and males.Physiological reports · 2022Article
- Sex differences in autonomic recovery following repeated sinusoidal resistance exercise.Physiological reports · 2022Article
- Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Patients With Heart Failure Supported With Continuous-Flow Left Ventricular Assist Devices.Circulation. Heart failure · 2021Article
- Does depth of squat-stand maneuver affect estimates of dynamic cerebral autoregulation?Physiological reports · 2020Article
- Physiological responses to a five-day adventure race: Continuous blood glucose, hemodynamics and metabolites the 2012 GODZone field-study.Journal of exercise science and fitness · 2018Article
- How many squat-stand manoeuvres to assess dynamic cerebral autoregulation?European journal of applied physiology · 2018Article
- Orthostatic heart rate changes in patients with autonomic failure caused by neurodegenerative synucleinopathies.Annals of neurology · 2018Article
- Relationship between blood pressure and cerebral blood flow during supine cycling: influence of aging.Journal of applied physiology (Bethesda, Md. : 1985) · 2016Article
- Methodological comparison of active- and passive-driven oscillations in blood pressure; implications for the assessment of cerebral pressure-flow relationships.Journal of applied physiology (Bethesda, Md. : 1985) · 2015Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
To assess baroreflex function under closed-loop conditions, a new approach was used to generate large and physiological perturbations in arterial pressure. Blood pressure (BP) and R-R interval were recorded continuously in 20 healthy young (33 +/- 8 yr) and eight elderly subjects (66 +/- 6 yr). Repeated squat-stand maneuvers at the frequencies of 0.05 and 0.1 Hz were performed to produce periodic oscillations in BP to provoke the baroreflex. To assess the effects of the muscle reflex and/or central command on the baroreflex, passive squat-stand maneuvers were conducted using a pulley system to assist changes in body position. Transfer function between changes in BP and R-R interval was estimated to assess the arterial-cardiac baroreflex. Relative to resting conditions, large and coherent oscillations in BP and R-R interval were produced during both active and passive squat-stand maneuvers. However, changes in BP were smaller during passive than during active maneuvers. Changes in R-R interval were reduced commensurately. Therefore, transfer function gain did not change between the two maneuvers. Compared with the young, transfer function gain was reduced and the phase became more negative in the elderly, demonstrating the well-known effects of aging on reducing baroreflex sensitivity. Collectively, these findings suggest that the changes in R-R interval elicited by BP perturbations during squat-stand maneuvers are mediated primarily by a baroreflex mechanism. Furthermore, baroreflex function can be assessed using the transfer function method during large perturbations in arterial pressure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.