Evidence map›Paper›PMID 19420059›Full record

ArticleNucleic acids research2009

Protinfo PPC: a web server for atomic level prediction of protein complexes.

Weerayuth Kittichotirat, Michal Guerquin, Roger E Bumgarner, Ram Samudrala

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Frontiers in molecular biosciences · 2021
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  8. Structural bioinformatics of the interactome.Annual review of biophysics · 2014
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. GWIDD: Genome-wide protein docking database.Nucleic acids research · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Weerayuth KittichotiratDepartment of Microbiology, University of Washington, Seattle, WA, USA.
Michal Guerquin
Roger E Bumgarner
Ram Samudrala
University of Washington · US

Funding

Novel clone-specific virulence determinants of A. actinomycetemcomitansR01DE012212 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, CASEY · 1999 to 2016
$5.0M
A cDNA Sequence Resource for BaboonR24RR021863 · NCRR · UNIVERSITY OF WASHINGTON · PI BUMGARNER, ROGER E. · 2006 to 2009
$2.4M
Combined Methods for Protein-Structure PredictionR01GM068570 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI KARPLUS, KEVIN · 2003 to 2007
$1.1M
NCRR NIH HHS 5R24RR021863NIDCR NIH HHS 5R01DE012212NIGMS NIH HHS 1 R01 GM068570-
6 · The paper itself

Abstract

'Protinfo PPC' (Prediction of Protein Complex) is a web server that predicts atomic level structures of interacting proteins from their amino-acid sequences. It uses the interolog method to search for experimental protein complex structures that are homologous to the input sequences submitted by a user. These structures are then used as starting templates to generate protein complex models, which are returned to the user in Protein Data Bank format via email. The server supports modeling of both homo and hetero multimers and generally produces full atomic level models (including insertion/deletion regions) of protein complexes as long as at least one putative homologous template for the query sequences is found. The modeling pipeline behind Protinfo PPC has been rigorously benchmarked and proven to produce highly accurate protein complex models. The fully automated all atom comparative modeling service for protein complexes provided by Protinfo PPC server offers wide capabilities ranging from prediction of protein complex interactions to identification of possible interaction sites, which will be useful for researchers studying these topics. The Protinfo PPC web server is available at http://protinfo.compbio.washington.edu/ppc/.

Indexed as

SoftwareDatabases, ProteinInternetModels, MolecularMultiprotein ComplexesProtein ConformationReproducibility of ResultsSequence Analysis, ProteinUser-Computer InterfaceMultiprotein Complexes

Identifiers

PMID19420059
PMCPMC2703994
OpenAlexW2133558054

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.