ArticleThe Journal of physiology2009
Location and properties of respiratory neurones with putative intrinsic bursting properties in the rat in situ.
Article in The Journal of physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 41 citations in OpenAlex.
- Asymmetric neuromodulation in the respiratory network contributes to rhythm and pattern generation.Frontiers in neural circuits · 2025Article
- Interdependence of cellular and network properties in respiratory rhythm generation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Interdependence of cellular and network properties in respiratory rhythmogenesis.bioRxiv : the preprint server for biology · 2023Article
- Advancing respiratory-cardiovascular physiology with the working heart-brainstem preparation over 25 years.The Journal of physiology · 2022Review
- Inhibitory control of active expiration by the Bötzinger complex in rats.The Journal of physiology · 2020Article
- Muscarinic Modulation of Morphologically Identified Glycinergic Neurons in the Mouse PreBötzinger Complex.Frontiers in cellular neuroscience · 2019Article
- Kinetic properties of persistent NaThe Journal of general physiology · 2018Article
- The interdependence of excitation and inhibition for the control of dynamic breathing rhythms.Nature communications · 2018Article
- The human ventilatory response to stress: rate or depth?The Journal of physiology · 2017Review
- Respiratory neuron characterization reveals intrinsic bursting properties in isolated adult turtle brainstems (Trachemys scripta).Respiratory physiology & neurobiology · 2016Article
- Neural Control of Breathing and CO2 Homeostasis.Neuron · 2015Review
- Regulation of breathing and autonomic outflows by chemoreceptors.Comprehensive Physiology · 2014Review
- Respiratory rhythm generation in vivo.Physiology (Bethesda, Md.) · 2014Review
- C1 neurons: the body's EMTs.American journal of physiology. Regulatory, integrative and comparative physiology · 2013Review
- Role of inhibition in respiratory pattern generation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Brainstem respiratory networks: building blocks and microcircuits.Trends in neurosciences · 2013Review
- The cellular building blocks of breathing.Comprehensive Physiology · 2012Review
- The role of spiking and bursting pacemakers in the neuronal control of breathing.Journal of biological physics · 2011Article
- Glycinergic pacemaker neurons in preBötzinger complex of neonatal mouse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Mylohyoid discharge of the in situ rat: a probe of pontile respiratory activities in eupnea and gasping.Journal of applied physiology (Bethesda, Md. : 1985) · 2010Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Using the in situ arterially perfused preparations of both neonatal and juvenile rats, we provide the first description of the location, morphology and transmitter content of a population of respiratory neurones that retains a bursting behaviour after ionotropic receptor blockade. All burster neurones exhibited an inspiratory discharge during eupnoeic respiration. These neurones were predominantly glutamatergic, and were located within a region of the ventral respiratory column that encompasses the pre-Bötzinger complex and the more caudally located ventral respiratory group. Bursting behaviour was both voltage and persistent sodium current dependent and could be stimulated by sodium cyanide to activate this persistent sodium current. The population of burster neurones may overlap with that previously described in the neonatal slice in vitro. Based upon the present and previous findings, we hypothesize that this burster discharge may be released when the brain is subject to severe hypoxia or ischaemia, and that this burster discharge could underlie gasping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.