ArticleNucleic acids research2009
Insignia: a DNA signature search web server for diagnostic assay development.
Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Seqwin: ultrafast identification of signature sequences in microbial genomes.Bioinformatics (Oxford, England) · 2026Article
- Seqwin: Ultrafast identification of signature sequences in microbial genomes.bioRxiv : the preprint server for biology · 2025Article
- AutoPVPrimer: A comprehensive AI-Enhanced pipeline for efficient plant virus primer design and assessment.PloS one · 2025Article
- Pitfalls of genotyping microbial communities with rapidly growing genome collections.Cell systems · 2023Article
- Trends in Molecular Diagnosis and Diversity Studies for Phytosanitary RegulatedMicroorganisms · 2021Review
- Article
- Detection and identification ofPeerJ · 2019Article
- Cluster oligonucleotide signatures for rapid identification by sequencing.BMC bioinformatics · 2018Article
- Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Article
- Neptune: a bioinformatics tool for rapid discovery of genomic variation in bacterial populations.Nucleic acids research · 2017Article
- HTSFinder: Powerful Pipeline of DNA Signature Discovery by Parallel and Distributed Computing.Evolutionary bioinformatics online · 2016Article
- DNA Sequence Signatures for Rapid Detection of Six Target Bacterial Pathogens Using PCR Assays.Microbiology insights · 2015Article
- An algorithm of discovering signatures from DNA databases on a computer cluster.BMC bioinformatics · 2014Article
- Repertoire of novel sequence signatures for the detection of Candidatus Liberibacter asiaticus by quantitative real-time PCR.BMC microbiology · 2014Article
- Pan-PCR, a computational method for designing bacterium-typing assays based on whole-genome sequence data.Journal of clinical microbiology · 2013Article
- Identification of DNA signatures suitable for use in development of real-time PCR assays by whole-genome sequence approaches: use of Streptococcus pyogenes in a pilot study.Journal of clinical microbiology · 2012Article
- A robust PCR primer design platform applied to the detection of Acidobacteria Group 1 in soil.Nucleic acids research · 2012Article
- Molecular probe technology detects bacteria without culture.BMC microbiology · 2012Article
- Evolutionary and experimental assessment of novel markers for detection of Xanthomonas euvesicatoria in plant samples.PloS one · 2012Article
- Alignment-free design of highly discriminatory diagnostic primer sets for Escherichia coli O104:H4 outbreak strains.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Insignia is a web application for the rapid identification of unique DNA signatures. DNA signatures are distinct nucleotide sequences that can be used to detect the presence of certain organisms and to distinguish those organisms from all other species. These signatures can be used as the basis for diagnostic assays to detect and genotype microbes in both environmental and clinical samples. Insignia identifies an exhaustive set of accurate DNA signatures for any set of target genomes, and screens these signatures against a comprehensive background that includes all sequenced bacteria and viruses, the human genome, and many other animals and plants. Identified signatures may be browsed by genomic location or proximal genes, filtered by composition, viewed in a genome browser or directly downloaded. Integrated PCR primer design is also provided for each signature. The Insignia website (http://insignia.cbcb.umd.edu) is free and open to all users and there is no login requirement. In addition, the source code for the computational pipeline is freely available.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.