Evidence map›Paper›PMID 19417051›Full record

ArticleJournal of the Royal Society of Medicine2009

The evolution of evidence hierarchies: what can Bradford Hill's 'guidelines for causation' contribute?

Jeremy Howick, Paul Glasziou, Jeffrey K Aronson

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the Royal Society of Medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03351712 (ACTonHEALTH Study Protocol), which is not on this map. Cited by 60 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03351712 naunknown statusnot on this mapstarted 2020, after this paper: background citation

ACTonHEALTH Study Protocol: Promoting Psychological Flexibility With Activity Tracker and mHealth Tools to Foster Healthy Lifestyle for Obesity and Other Chronic Health Conditions

TypeinterventionalSponsorIstituto Auxologico ItalianoRan2020 to 2024Enrolled60ConditionsHealth BehaviorArmsACT-Based Intervention and Activity Tracker WITH Feedback, Gold Standard Intervention + Activity Tracker WITHOUT Feedback, Gold Standard Intervention and Activity Tracker WITH Feedback, ACT-Based Intervention and Activity Tracker WITHOUT Feedback
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  5. Signals were broadly positive for months, but never definitive: the tocilizumab story.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeremy HowickCentre for Evidence-Based Medicine, Rosemary Rue Building, Old Road Campus, University of Oxford Oxford OX3 7LF. Jeremy.howick@dphpc.ox.ac.uk
Paul Glasziou
Jeffrey K Aronson

Funding

Medical Research Council G0800055
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical Trials as TopicEvidence-Based MedicineGuidelines as TopicTreatment Outcome

Identifiers

PMID19417051
PMCPMC2677430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.