ArticleGeneral and comparative endocrinology2009
Seasonal relationship between gonadotropin, growth hormone, and estrogen receptor mRNA expression in the pituitary gland of largemouth bass.
Article in General and comparative endocrinology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 54 citations in OpenAlex.
- Tissue and maturation specific DNA methylation dynamics of gonadotropin genes in chub mackerel (Scomber japonicus) using cost-effective targeted bisulfite sequencing.Scientific reports · 2026Article
- Steroidogenic acute regulatory protein in fish.The Journal of endocrinology · 2025Review
- The PCOS-NAFLD Multidisease Phenotype Occurred in Medaka Fish Four Generations after the Removal of Bisphenol A Exposure.Environmental science & technology · 2023Article
- Out-of-season spawning of largemouth bass in a controllable recirculating system.Frontiers in physiology · 2023Article
- Declines in Reproductive Condition of Male Largemouth Bass (International journal of molecular sciences · 2022Article
- Steroidogenic acute regulatory protein transcription is regulated by estrogen receptor signaling in largemouth bass ovary.General and comparative endocrinology · 2020Article
- Spexin and a Novel Cichlid-Specific Spexin Paralog Both Inhibit FSH and LH Through a Specific Galanin Receptor (Galr2b) in Tilapia.Frontiers in endocrinology · 2020Article
- Understanding pseudo-albinism in sole (Solea senegalensis): a transcriptomics and metagenomics approach.Scientific reports · 2019Article
- Dietary exposure of 17-alpha ethinylestradiol modulates physiological endpoints and gene signaling pathways in female largemouth bass (Micropterus salmoides).Aquatic toxicology (Amsterdam, Netherlands) · 2014Article
- Gene expression networks underlying ovarian development in wild largemouth bass (Micropterus salmoides).PloS one · 2013Article
- Identification and transcriptional modulation of the largemouth bass, Micropterus salmoides, vitellogenin receptor during oocyte development by insulin and sex steroids.Biology of reproduction · 2012Article
- Cloning and expression of the translocator protein (18 kDa), voltage-dependent anion channel, and diazepam binding inhibitor in the gonad of largemouth bass (Micropterus salmoides) across the reproductive cycle.General and comparative endocrinology · 2011Article
- Methoxychlor affects multiple hormone signaling pathways in the largemouth bass (Micropterus salmoides) liver.Aquatic toxicology (Amsterdam, Netherlands) · 2011Article
- Gene structure, transcripts and calciotropic effects of the PTH family of peptides in Xenopus and chicken.BMC evolutionary biology · 2010Article
- Effects of acute dieldrin exposure on neurotransmitters and global gene transcription in largemouth bass (Micropterus salmoides) hypothalamus.Neurotoxicology · 2010Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The objectives of this study were to investigate the seasonal changes in pituitary gonadotropins, growth hormone (GH), and estrogen receptor (ER) isoform mRNA in wild female and male largemouth bass (LMB) (Micropterus salmoides) from an unpolluted habitat to better understand reproductive physiology in this ecologically important species. Female pituitary luteinizing hormone (LH) beta subunit and follicle stimulating hormone (FSH) beta subunit mRNA showed significant seasonal variation with levels peaking from January to April and were lowest from May to August. Male LMB showed more variation in gonadotropin subunit expression from month to month. Females had approximately 2-3 times higher gonadotropin mRNA levels in the pituitary when compared to males. All three gonadotropin mRNAs in females were positively correlated to gonadosomatic index (GSI), but only LHbeta mRNA was correlated to GSI in males. Gonadotropin mRNA expression also increased with increasing oocyte and sperm maturation. Gonadotropin beta subunit mRNA expression was positively correlated to GH mRNA in both sexes. The expression of all three ER isoforms was significantly correlated to each other in both sexes. The concurrent increase in all three ER mRNA isoforms with increasing gonadotropin mRNA in females and males suggests a prominent role for E2 feedback on pituitary gonadotropin synthesis in both sexes and that each of the three ER isoforms are likely to play a role in the pituitary during teleost reproduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.