Evidence map›Paper›PMID 19416065›Full record

ReviewAnnual review of biophysics2009

Imaging transcription in living cells.

Xavier Darzacq, Jie Yao, Daniel R Larson, Sébastien Z Causse, Lana Bosanac, Valeria de Turris, Vera M Ruda, Timothee Lionnet, Daniel Zenklusen, Benjamin Guglielmi and 2 more

Abstract readReview
In one paragraph

Review in Annual review of biophysics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Quantifying Single mRNA Translation Kinetics in Living Cells.Cold Spring Harbor perspectives in biology · 2018
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Transcription Dynamics in Living Cells.Annual review of biophysics · 2016
    Review
  18. Review
  19. Article
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xavier DarzacqJanelia Farm Research Consortium on Imaging Transcription, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA. darzacq@ens.fr
Jie Yao
Daniel R Larson
Sébastien Z Causse
Lana Bosanac
Valeria de Turris
Vera M Ruda
Timothee Lionnet
Daniel Zenklusen
Benjamin Guglielmi
Robert Tjian
Robert H Singer

Funding

LIGHT-ACTIVATED GENE EXPRESSION IN SINGLE CELLS WITHIN TISSUER01GM086217 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SINGER, ROBERT H · 2008 to 2011
$2.9M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM086217
6 · The paper itself

Abstract

The advent of new technologies for the imaging of living cells has made it possible to determine the properties of transcription, the kinetics of polymerase movement, the association of transcription factors, and the progression of the polymerase on the gene. We report here the current state of the field and the progress necessary to achieve a more complete understanding of the various steps in transcription. Our Consortium is dedicated to developing and implementing the technology to further this understanding.

Indexed as

Gene Expression ProfilingImage Interpretation, Computer-AssistedMicroscopy, FluorescenceTranscriptional ActivationTranscription FactorsTranscription Factors

Identifiers

PMID19416065
PMCPMC3166783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.