ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2009
Molecular diagnostics of intestinal parasites in returning travellers.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 5 of them syntheses that pooled it.
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Who cites it
64 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- IvermectinParasitology · 2024Pooled it
- Prevalence of intestinal protozoan parasites among school children in africa: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2022Pooled it
- Accuracy of molecular biology techniques for the diagnosis of Strongyloides stercoralis infection-A systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection.The Cochrane database of systematic reviews · 2016Pooled it
- The laboratory diagnosis and follow up of strongyloidiasis: a systematic review.PLoS neglected tropical diseases · 2013Pooled it
- Detection of soil-transmitted helminths and Schistosoma spp. by nucleic acid amplification test: Results of the first 5 years of the only international external quality assessment scheme.PLoS neglected tropical diseases · 2024Article
- Intestinal protozoa in returning travellers: a GeoSentinel analysis from 2007 to 2019.Journal of travel medicine · 2024Article
- Molecular Characterization ofArchives of Razi Institute · 2024Article
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- Diagnosis of protozoa diarrhoea in Campylobacter patients increases markedly with molecular techniques.PLOS global public health · 2023Article
- Prevalence of Human IntestinalPathogens (Basel, Switzerland) · 2022Review
- Colitis caused by Entamoeba histolytica identified by real-time-PCR and fluorescence in situ hybridization from formalin-fixed, paraffin-embedded tissue.European journal of microbiology & immunology · 2022Article
- Diagnostic Methods of Common Intestinal Protozoa: Current and Future Immunological and Molecular Methods.Tropical medicine and infectious disease · 2022Review
- Evaluation of a Novel Commercial Real-Time PCR Assay for the Simultaneous Detection ofMicrobiology spectrum · 2022Article
- Article
- Article
- Selecting a multiplex PCR panel for accurate molecular diagnosis of intestinal protists: a comparative study of AllplexParasite (Paris, France) · 2022Article
- Membrane Technology for Rapid Point-of-Care Diagnostics for Parasitic Neglected Tropical Diseases.Clinical microbiology reviews · 2021Article
- Comparison of Three Real-Time PCR Assays Targeting the SSU rRNA Gene, the COWP Gene and the DnaJ-Like Protein Gene for the Diagnosis ofPathogens (Basel, Switzerland) · 2021Article
- New Developments in PCR-Based Diagnostics for Bacterial Pathogens Causing Gastrointestinal Infections-A Narrative Mini-Review on Challenges in the Tropics.Tropical medicine and infectious disease · 2021Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new diagnostic strategy was assessed for the routine diagnosis of intestinal parasites in returning travellers and immigrants. Over a period of 13 months, unpreserved stool samples, patient characteristics and clinical data were collected from those attending a travel clinic. Stool samples were analysed on a daily basis by microscopic examination and antigen detection (i.e. care as usual), and compared with a weekly performed multiplex real-time polymerase chain reaction (PCR) analysis on Entamoeba histolytica, Giardia lamblia, Cryptosporidium and Strongyloides stercoralis. Microscopy and antigen assays of 2,591 stool samples showed E. histolytica, G. lamblia, Cryptosporidium and S. stercoralis in 0.3, 4.7, 0.5 and 0.1% of the cases, respectively. These detection rates were increased using real-time PCR to 0.5, 6.0, 1.3 and 0.8%, respectively. The prevalence of ten additional pathogenic parasite species identified with microscopy was, at most, 0.5%. A pre-selective decision tree based on travel history or gastro-intestinal complaints could not be made. With increased detection rates at a lower workload and the potential to extend with additional parasite targets combined with fully automated DNA isolation, molecular high-throughput screening could eventually replace microscopy to a large extent.
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Registered trials
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