ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2009
Involvement of Müller glial cells in epiretinal membrane formation.
Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 2 syntheses or guidelines pooled it, 190 citations in OpenAlex.
- SURGICAL OUTCOMES OF LAMELLAR MACULAR HOLE EYES WITH OR WITHOUT PRESERVATION OF LAMELLAR HOLE-ASSOCIATED EPIRETINAL PROLIFERATION TECHNIQUE: A Meta-analysis.Retina (Philadelphia, Pa.) · 2025Pooled it
- With or without internal limiting membrane peeling during idiopathic epiretinal membrane surgery: A meta-analysis.PloS one · 2021Pooled it
- Macular peeling-induced retinal damage: clinical and histopathological evaluation after using different dyes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018Trial
- Retinal glial cell removing during internal limiting membrane peeling is associated with higher-stage idiopathic epiretinal membrane.Eye and vision (London, England) · 2026Article
- Lipid nanoparticles enable mRNA delivery to diverse cell types of the inner Retina.Molecular therapy. Nucleic acids · 2026Article
- Human single-cell atlas of proliferative diabetic retinopathy reveals a SOX15-overexpressing stromal population driving retinal fibrosis through the endothelin-1 -EDNRB axis.Journal of translational medicine · 2026Article
- Association of epiretinal membranes with disability in people with multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- Clinical and Imaging Characteristics of Thin and Thick Idiopathic Epiretinal Membranes Assessed by High-Resolution OCT.Investigative ophthalmology & visual science · 2026Article
- Response to: Comment on: "Epiretinal membrane formation and incomplete separation of the posterior hyaloid membrane".Eye (London, England) · 2026Article
- Novel Systemic Associations of Idiopathic Epiretinal Membrane Identified via Machine Learning.Ophthalmology science · 2026Article
- Correlation of retinal imaging with presence of inner limiting membrane pores in idiopathic epiretinal gliosis.International journal of retina and vitreous · 2026Article
- The existence of puckering in the retina beyond the macula: a prospective analysis.International ophthalmology · 2026Article
- Substrate stiffness and pressure alter retinal Müller glia response and extracellular matrix production.Biomaterials and biosystems · 2025Article
- Hyperreflective Foci in the Ectopic Inner Foveal Layer of Advanced Idiopathic Epiretinal Membranes.Investigative ophthalmology & visual science · 2025Article
- A pilot study of intraoperative melphalan to prevent recurrent PVR: the IOMPVR study.International journal of retina and vitreous · 2025Article
- Evaluation of blood-count-derived inflammatory markers in patients with idiopathic epiretinal membrane.BMC ophthalmology · 2025Article
- Topographic relationship between glial cells and neovessels of the epiretinal membrane in proliferative diabetic retinopathy depends on the phase of angiogenesis.Frontiers in cellular neuroscience · 2025Article
- Aqueous Humor Cytokines in Idiopathic Epiretinal Membrane: Correlation with Disease Severity.Diagnostics (Basel, Switzerland) · 2024Article
- Epiretinal membranes in patients with uveitis: an update on the current state of management.International ophthalmology · 2024Review
- Crosstalk Between Microglia and Müller Glia in the Age-Related Macular Degeneration: Role and Therapeutic Value of Neuroinflammation.Aging and disease · 2024Review
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProliferative retinopathies are considered to represent maladapted retinal wound repair processes driven by growth factor- and cytokine-induced overstimulation of proliferation, migration, extracellular matrix production and contraction of retinal cells. The formation of neovascular membranes represents an attempt to reoxygenize non-perfused retinal areas. Müller glial cells play a crucial role in the pathogenesis of proliferative retinopathies. This review summarizes the present knowledge regarding the role of Müller cells in periretinal membrane formation, especially in the early steps of epiretinal membrane formation, which involve an interaction of inflammatory and glial cells, and gives a survey of the factors which are suggested to be implicated in the induction of Müller cell gliosis and proliferation.
conclusionsAlterations in the membrane conductance of Müller cells suggest that Müller cells may alter their phenotype into progenitor-like cells in the course of proliferative retinopathies; transdifferentiated Müller cells may have great impact for the development of new cell-based therapies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.