ArticleArchives of general psychiatry2009
Depressive symptom dimensions and cardiovascular prognosis among women with suspected myocardial ischemia: A report from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation.
Article in Archives of general psychiatry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Changes in cognitive versus somatic symptoms of depression and event-free survival following acute myocardial infarction in the Enhancing Recovery In Coronary Heart Disease (ENRICHD) study.Journal of affective disorders · 2013Trial
- Latest from the WISE: Contributions to the Understanding of Ischemia and Heart Failure among Women with No Obstructive Coronary Arteries.Reviews in cardiovascular medicine · 2023Review
- Longitudinal change and prognostic value of anxiety and depression in coronary heart disease patients.Irish journal of medical science · 2021Article
- Predisposition of Women to Cardiovascular Diseases: A Side-Effect of Increased Glucocorticoid Signaling During the COVID-19 Pandemic?Frontiers in global women's health · 2021Review
- Even "WISE-R?"-an Update on the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation.Current atherosclerosis reports · 2020Review
- Depressive symptoms in patients with obstructive sleep apnea: biological mechanistic pathways.Journal of behavioral medicine · 2017Article
- Depressive symptoms, functional measures and long-term outcomes of high-risk ST-elevated myocardial infarction patients treated by primary angioplasty.Internal and emergency medicine · 2017Article
- Article
- Beta-adrenergic receptor mediated inflammation control by monocytes is associated with blood pressure and risk factors for cardiovascular disease.Brain, behavior, and immunity · 2015Article
- Depression in people with coronary heart disease: prognostic significance and mechanisms.Current cardiology reports · 2015Review
- Depression in Cardiovascular Patients in Middle Eastern Populations: A Literature Review.Journal of immigrant and minority health · 2015Review
- Depressive symptoms effect on self care behavior during the first month after myocardial infarction.Global journal of health science · 2015Article
- Somatic, but not cognitive-affective, symptoms are associated with reduced heart rate variability in individuals with dysphoria.Frontiers in psychology · 2015Article
- Late-life depression and cardiovascular disease burden: examination of reciprocal relationship.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2014Article
- Felt age and cognitive-affective depressive symptoms in late life.Aging & mental health · 2014Article
- Depressive symptoms are associated with allostatic load among community-dwelling older adults.Physiology & behavior · 2014Article
- The combined association of depression and socioeconomic status with length of post-operative hospital stay following coronary artery bypass graft surgery: data from a prospective cohort study.Journal of psychosomatic research · 2014Article
- The predictive value of somatic and cognitive depressive symptoms for cytokine changes in patients with major depression.Neuropsychiatric disease and treatment · 2014Article
- Evaluating the impact of depression, anxiety & autonomic function on health related quality of life, vocational functioning and health care utilisation in acute coronary syndrome patients: the ADVENT study protocol.BMC cardiovascular disorders · 2013Article
- Clinical implications of the Women's Ischemia Syndrome Evaluation: inter-relationships between symptoms, psychosocial factors and cardiovascular outcomes.Women's health (London, England) · 2013Review
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Authors and funding
11 authors.
Funding
Abstract
contextSymptoms of depression and cardiovascular disease (CVD) overlap substantially. Differentiating between dimensions of depressive symptoms may improve our understanding of the relationship between depression and physical health.
objectiveTo compare symptom dimensions of depression as predictors of cardiovascular-related death and events among women with suspected myocardial ischemia.
designCohort study of women with suspected myocardial ischemia who underwent evaluation at baseline for a history of cardiovascular-related problems, depressive symptoms using the Beck Depression Inventory, and coronary artery disease severity via coronary angiography. Principal components analyses (PCAs) of the Beck Depression Inventory items were conducted to examine differential cardiovascular prognosis according to symptom dimensions of depression.
settingThe Women's Ischemia Syndrome Evaluation (WISE), a multicenter study sponsored by the National Heart, Lung, and Blood Institute to assess cardiovascular function using state-of-the-art techniques in women referred for coronary angiography to evaluate chest pain or suspected myocardial ischemia.
participantsFive hundred fifty women (mean [SD] age, 58.4 [11.2] years) enrolled in the WISE study and followed up for a median of 5.8 years.
main outcome measuresCardiovascular-related mortality and events (stroke, myocardial infarction, and congestive heart failure).
resultsWhen a 3-factor structure from PCA was used, somatic/affective (hazards ratio, 1.35; 95% confidence interval, 1.04-1.74) and appetitive (1.42; 1.21-1.68) but not cognitive/affective (0.89; 0.70-1.14) symptoms predicted cardiovascular prognosis in adjusted multivariate Cox regression analysis. When a 2-factor structure from PCA was used, adjusted results indicated that somatic (hazards ratio, 1.63; 95% confidence interval, 1.28-2.08) but not cognitive/affective (0.87; 0.68-1.11) symptoms predicted worse prognosis.
conclusionsIn a sample of women with suspected myocardial ischemia, somatic but not cognitive/affective depressive symptoms were associated with an increased risk of cardiovascular-related mortality and events. These results support the need to research dimensions of depression in CVD populations and have implications for understanding the connection between depression and CVD.
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