ArticlePhilosophical transactions. Series A, Mathematical, physical, and engineering sciences2009
Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples.
Article in Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Distributed and networked analysis of volumetric image data for remote collaboration of microscopy image analysis.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Quantifying and Visualizing Uncertainty for Source Localization in Electrocardiographic Imaging.Computer methods in biomechanics and biomedical engineering. Imaging & visualization · 2023Article
- Tipping the scales of understanding: An engineering approach to design and implement whole-body cardiac electrophysiology experimental models.Frontiers in physiology · 2023Article
- Calibration of ionic and cellular cardiac electrophysiology models.Wiley interdisciplinary reviews. Systems biology and medicine · 2020Review
- A Framework for Image-Based Modeling of Acute Myocardial Ischemia Using Intramurally Recorded Extracellular Potentials.Annals of biomedical engineering · 2018Article
- Sensitivity analysis of ventricular activation and electrocardiogram in tailored models of heart-failure patients.Medical & biological engineering & computing · 2018Article
- The Consortium for Electrocardiographic Imaging.Computing in cardiology · 2016Article
- Epileptogenic focus localization in treatment-resistant post-traumatic epilepsy.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2015Review
- Patient-specific modelling of cardiac electrophysiology in heart-failure patients.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2014Article
- Images as drivers of progress in cardiac computational modelling.Progress in biophysics and molecular biology · 2014Review
- Sensitivity and specificity of substrate mapping: an in silico framework for the evaluation of electroanatomical substrate mapping strategies.Journal of cardiovascular electrophysiology · 2014Article
- Biomedical Visual Computing: Case Studies and Challenges.Computing in science & engineering · 2012Article
- A macro finite-element formulation for cardiac electrophysiology simulations using hybrid unstructured grids.IEEE transactions on bio-medical engineering · 2011Article
- Image-based modeling of acute myocardial ischemia using experimentally derived ischemic zone source representations.Journal of electrocardiologyArticle
- Electrographic Response of the Heart to Myocardial Ischemia.Computers in cardiologyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Many simulation studies in biomedicine are based on a similar sequence of processing steps, starting from images and running through geometric model generation, assignment of tissue properties, numerical simulation and visualization of the results--a process known as image-based geometric modelling and simulation. We present an overview of software systems for implementing such a sequence both within highly integrated problem-solving environments and in the form of loosely integrated pipelines. Loose integration in this case indicates that individual programs function largely independently but communicate through files of a common format and support simple scripting, so as to automate multiple executions wherever possible. We then describe three specific applications of such pipelines to translational biomedical research in electrophysiology.
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