ReviewUrologic oncology
Identification, characterization, and biological relevance of prostate cancer stem cells from clinical specimens.
Review in Urologic oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Unravelling therapeutic resistance: role of cancer stem cell and microRNA in metastatic prostate cancer.Frontiers in molecular biosciences · 2026Review
- Effects of Sorafenib, a Tyrosin Kinase Inhibitor, on Adrenocortical Cancer.Frontiers in endocrinology · 2021Article
- Prostate Cancer Stem Cell Markers Drive Progression, Therapeutic Resistance, and Bone Metastasis.Stem cells international · 2017Review
- Current Stem Cell Biomarkers and Their Functional Mechanisms in Prostate Cancer.International journal of molecular sciences · 2016Review
- Role of Sonic Hedgehog (Shh) Signaling in Bladder Cancer Stemness and Tumorigenesis.Current urology reports · 2016Review
- Role of BioResponse 3,3'-Diindolylmethane in the Treatment of Human Prostate Cancer: Clinical Experience.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2016Review
- MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell.BMC cancer · 2014Article
- Overview of cancer stem cells (CSCs) and mechanisms of their regulation: implications for cancer therapy.Current protocols in pharmacology · 2013Review
- Novel strategies targeting cancer stem cells through phytochemicals and their analogs.Drug delivery and translational research · 2013Article
- A novel in vitro model for cancer stem cell culture using ectopically expressed piwil2 stable cell line.Cell journal · 2013Article
- Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus.PloS one · 2013Article
- Actions of estrogens and endocrine disrupting chemicals on human prostate stem/progenitor cells and prostate cancer risk.Molecular and cellular endocrinology · 2012Review
- The cancer stem cell niche--there goes the neighborhood?International journal of cancer · 2011Review
- Integrin αv expression is required for the acquisition of a metastatic stem/progenitor cell phenotype in human prostate cancer.The American journal of pathology · 2011Article
- The aldehyde dehydrogenase enzyme 7A1 is functionally involved in prostate cancer bone metastasis.Clinical & experimental metastasis · 2011Article
- Expression of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration.The Prostate · 2011Article
- Article
- Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?Cancers · 2011Article
- Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells.PloS one · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Cancer stem cells (CSCs) are a reservoir of tumor cells that exhibit the properties of self-renewal and the ability to re-establish the heterogeneous cell population of a tumor. They appear therapy-resistant and may be the underlying cause of recurrent disease. Using prostate as a model, this review presents the CSC hypothesis and discusses the role of the androgen receptor in CSCs, the methods used for isolating CSCs, and the therapeutic challenges CSCs have for cancer therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.