ArticleBiophysical journal2009
Activity correlation imaging: visualizing function and structure of neuronal populations.
Article in Biophysical journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 56 citations in OpenAlex.
- Imaging neuronal voltage beyond the scattering limit.Nature methods · 2025Article
- A distinct hypothalamus-habenula circuit governs risk preference.Nature neuroscience · 2025Article
- Centripetal integration of past events in hippocampal astrocytes regulated by locus coeruleus.Nature neuroscience · 2024Article
- Calcium imaging of adult olfactory epithelium reveals amines as important odor class in fish.Cell and tissue research · 2024Article
- Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.Nature microbiology · 2023Article
- Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae.Scientific reports · 2021Article
- Article
- Three dimensional two-photon brain imaging in freely moving mice using a miniature fiber coupled microscope with active axial-scanning.Scientific reports · 2018Article
- All-Optical Assay to Study Biological Neural Networks.Frontiers in neuroscience · 2018Article
- Coordinated shift of olfactory amino acid responses and V2R expression to an amphibian water nose during metamorphosis.Cellular and molecular life sciences : CMLS · 2017Article
- Functional Reintegration of Sensory Neurons and Transitional Dendritic Reduction of Mitral/Tufted Cells during Injury-Induced Recovery of the LarvalFrontiers in cellular neuroscience · 2017Article
- Automated Functional Analysis of Astrocytes from Chronic Time-Lapse Calcium Imaging Data.Frontiers in neuroinformatics · 2017Article
- SamuROI, a Python-Based Software Tool for Visualization and Analysis of Dynamic Time Series Imaging at Multiple Spatial Scales.Frontiers in neuroinformatics · 2017Article
- One Special Glomerulus in the Olfactory Bulb of Xenopus laevis Tadpoles Integrates a Broad Range of Amino Acids and Mechanical Stimuli.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis.Journal of visualized experiments : JoVE · 2016Article
- Remote z-scanning with a macroscopic voice coil motor for fast 3D multiphoton laser scanning microscopy.Biomedical optics express · 2016Article
- Different expression domains for two closely related amphibian TAARs generate a bimodal distribution similar to neuronal responses to amine odors.Scientific reports · 2015Article
- Integrating temperature with odor processing in the olfactory bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- An excitatory GABA loop operating in vivo.Frontiers in cellular neuroscience · 2015Article
- Purinergic receptor-induced Ca2+ signaling in the neuroepithelium of the vomeronasal organ of larval Xenopus laevis.Purinergic signalling · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For the analysis of neuronal networks it is an important yet unresolved task to relate the neurons' activities to their morphology. Here we introduce activity correlation imaging to simultaneously visualize the activity and morphology of populations of neurons. To this end we first stain the network's neurons using a membrane-permeable [Ca(2+)] indicator (e.g., Fluo-4/AM) and record their activities. We then exploit the recorded temporal activity patterns as a means of intrinsic contrast to visualize individual neurons' dendritic morphology. The result is a high-contrast, multicolor visualization of the neuronal network. Taking the Xenopus olfactory bulb as an example we show the activities of the mitral/tufted cells of the olfactory bulb as well as their projections into the olfactory glomeruli. This method, yielding both functional and structural information of neuronal populations, will open up unprecedented possibilities for the investigation of neuronal networks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.