Evidence map›Paper›PMID 19413510›Full record

ReviewAnnual review of biomedical engineering2009

Living-cell microarrays.

Martin L Yarmush, Kevin R King

Abstract readReview
In one paragraph

Review in Annual review of biomedical engineering, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Living Cell Microarrays: An Overview of Concepts.Microarrays (Basel, Switzerland) · 2016
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Block-Cell-Printing for live single-cell printing.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Martin L YarmushCenter for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Harvard Medical School, Massachusetts 02139, USA. ireis@sbi.org
Kevin R King

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
Bio-MicroElectroMechanical Systems Resource CenterP41EB002503 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 2004 to 2018
$17.4M
Living Cell Arrays for Real Time Functional GenomicsR01AI063795 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI YARMUSH, MARTIN L · 2005 to 2009
$3.3M
NIAID NIH HHS R01 AI063795NIBIB NIH HHS P41 EB002503NIBIB NIH HHS P41EB002503NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

Living cells are remarkably complex. To unravel this complexity, living-cell assays have been developed that allow delivery of experimental stimuli and measurement of the resulting cellular responses. High-throughput adaptations of these assays, known as living-cell microarrays, which are based on microtiter plates, high-density spotting, microfabrication, and microfluidics technologies, are being developed for two general applications: (a) to screen large-scale chemical and genomic libraries and (b) to systematically investigate the local cellular microenvironment. These emerging experimental platforms offer exciting opportunities to rapidly identify genetic determinants of disease, to discover modulators of cellular function, and to probe the complex and dynamic relationships between cells and their local environment.

Indexed as

Microfluidic Analytical TechniquesMicrofluidicsAnimalsCell Culture TechniquesCellular StructuresGenomicsGreen Fluorescent ProteinsHumansMagneticsMicrotechnologyOligonucleotide Array Sequence AnalysisRNA InterferenceTime FactorsTransfectionGreen Fluorescent Proteins

Identifiers

PMID19413510
PMCPMC3208259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.