Evidence map›Paper›PMID 19412619›Full record

ReviewChromosoma2009

Constitutive heterochromatin: a surprising variety of expressed sequences.

Patrizio Dimitri, Ruggiero Caizzi, Ennio Giordano, Maria Carmela Accardo, Giovanna Lattanzi, Giuseppe Biamonti

Abstract readReview
PubMed Publisher
In one paragraph

Review in Chromosoma, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. The Green Valley ofCells · 2022
    Review
  3. Chromosomal Diversification inAnimals : an open access journal from MDPI · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. Comparative Cytogenetics Analysis AmongFrontiers in genetics · 2021
    Article
  8. Article
  9. Article
  10. A combined banding method that allows the reliable identification of chromosomes as well as differentiation of AT- and GC-rich heterochromatin.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Patrizio DimitriLaboratorio di Genomica Funzionale e Proteomica di Sistemi modello and Istituto Pasteur-Fondazione Bolognetti, Dipartimento di Genetica e Biologia Molecolare Charles Darwin, Università La Sapienza, 00185, Italy. patrizio.dimitri@uniroma1.it
Ruggiero Caizzi
Ennio Giordano
Maria Carmela Accardo
Giovanna Lattanzi
Giuseppe Biamonti
Istituto di Genetica Molecolare · ITIstituto Pasteur · ITSapienza University of Rome · ITUniversity of Bari Aldo Moro · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The organization of chromosomes into euchromatin and heterochromatin is amongst the most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is a basic yet still poorly understood component of eukaryotic chromosomes, and its molecular characterization by means of standard genomic approaches is intrinsically difficult. Although recent evidence indicates that the presence of transcribed genes in constitutive heterochromatin is a conserved trait that accompanies the evolution of eukaryotic genomes, the term heterochromatin is still considered by many as synonymous of gene silencing. In this paper, we comprehensively review data that provide a clearer picture of transcribed sequences within constitutive heterochromatin, with a special emphasis on Drosophila and humans.

Indexed as

Gene ExpressionAnimalsChromosome MappingDrosophila melanogasterHeterochromatinHumansIn Situ Hybridization, FluorescenceHeterochromatin

Identifiers

PMID19412619
OpenAlexW2093833918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.