ArticleAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2009
Intracranial and blood pressure variability and long-term outcome after aneurysmal sub-arachnoid hemorrhage.
Article in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intracranial hypertension in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis.Neurosurgical review · 2021Pooled it
- Electric versus manual tooth brushing among neuroscience ICU patients: is it safe?Neurocritical care · 2011Trial
- Exploring the Association of Systolic Blood Pressure and Intracranial Pressure Variability and Subarachnoid Hemorrhage Patient Outcomes.Journal of clinical medicine · 2026Article
- Blood Pressure Variability in Acute Stroke: A Narrative Review.Journal of clinical medicine · 2024Review
- Association between blood pressure control during aneurysm clipping and functional outcomes in patients with aneurysmal subarachnoid hemorrhage.Frontiers in neurology · 2024Article
- Association of Blood Pressure Variability with Delirium in Patients with Critical Illness.Neurocritical care · 2023Observational
- Intracranial and Blood Pressure Variability and In-Hospital Outcomes in Intracranial Device-Monitored Patients with Spontaneous Intracerebral Hemorrhage.Neurocritical care · 2023Article
- Association of Blood Pressure Variability With Death and Discharge Destination Among Critically Ill Patients With and Without Stroke.Neurology · 2023Article
- Higher intracranial pressure variability is associated with lower cerebrovascular resistance in aneurysmal subarachnoid hemorrhage.Journal of clinical monitoring and computing · 2023Observational
- Low intracranial pressure variability is associated with delayed cerebral ischemia and unfavorable outcome in aneurysmal subarachnoid hemorrhage.Journal of clinical monitoring and computing · 2022Article
- Changes in nonlinear dynamic complexity measures of blood pressure during anesthesia for cardiac surgeries using cardio pulmonary bypass.Journal of clinical monitoring and computing · 2020Observational
- Association between blood pressure variability and the short-term outcome in patients with acute spontaneous subarachnoid hemorrhage.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Complexity of preoperative blood pressure dynamics: possible utility in cardiac surgical risk assessment.Journal of clinical monitoring and computing · 2019Observational
- Blood pressure variability: can nonlinear dynamics enhance risk assessment during cardiovascular surgery?Journal of cardiothoracic and vascular anesthesia · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundCare of brain-injured patients in intensive care units has focused on maintaining arterial blood pressure and intracranial pressure within prescribed ranges. Research suggests, however, that the dynamic variability of these pressure signals provides additional information about physiological functioning and may reflect adaptive capacity.
objectivesTo see if long-term outcomes can be predicted from variability of arterial blood pressure and intracranial pressure in patients with aneurysmal subarachnoid hemorrhage.
methodsArterial blood pressure and intracranial pressure were monitored continuously for 4 days in 90 patients (74% women; mean age, 53 years) in an intensive care unit after subarachnoid hemorrhage. Variability of arterial blood pressure and intracranial pressure signals was calculated on 4 timescales: 24 hours, 1 hour, 5 minutes, and the difference of sequential 5-second means. The Extended Glasgow Outcome Scale was used to assess functional outcome 6 months after subarachnoid hemorrhage.
resultsPressure variability was better than mean pressure levels for predicting 6-month functional outcome. When initial neurological condition was controlled for, greater faster variability (particularly 5-second) was associated with better outcomes (typical P<.001), whereas greater 24-hour variability was associated with poorer outcomes (typical P<.001).
conclusionsThe relationship between long-term functional outcome and variability of arterial blood pressure and intracranial pressure levels depends on the timescale at which the variability is measured. Because it is associated with better outcome, greater faster variability may reflect better physiological adaptive capacity.
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