Evidence map›Paper›PMID 19411411›Full record

ArticleApplied and environmental microbiology2009

Identification of a novel alkaliphilic esterase active at low temperatures by screening a metagenomic library from antarctic desert soil.

Caroline Heath, Xiao Ping Hu, S Craig Cary, Donald Cowan

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Recent Advances in Function-based Metagenomic Screening.Genomics, proteomics & bioinformatics · 2018
    Review
  7. Article
  8. Review
  9. Metagenomics: Retrospect and Prospects in High Throughput Age.Biotechnology research international · 2015
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. New extremophilic lipases and esterases from metagenomics.Current protein & peptide science · 2014
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Caroline HeathDepartment of Biotechnology, University of the Western Cape, Cape Town, South Africa.
Xiao Ping Hu
S Craig Cary
Donald Cowan
University of the Western Cape · ZAUniversity of Waikato · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel esterase was identified through functional screening of a metagenomic library in Escherichia coli obtained from Antarctic desert soil. The 297-amino-acid sequence had only low (<29%) similarity to a putative esterase from Burkholderia xenovorans. The enzyme was active over a temperature range of 7 to 54 degrees C and at alkaline pH levels and is a potential candidate for industrial application.

Indexed as

Soil MicrobiologyAntarctic RegionsBurkholderiaDNAEnzyme StabilityEscherichia coliEsterasesGene ExpressionHydrogen-Ion ConcentrationMolecular Sequence DataSequence Analysis, DNASequence Homology, Amino AcidTemperatureDNAEsterases

Identifiers

PMID19411411
PMCPMC2704825
OpenAlexW2056362040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.