Trial reportGeneral hospital psychiatry
The Indiana Cancer Pain and Depression (INCPAD) trial Design of a telecare management intervention for cancer-related symptoms and baseline characteristics of study participants.
Trial report in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Automated telephone communication systems for preventive healthcare and management of long-term conditions.The Cochrane database of systematic reviews · 2016Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- Citalopram versus other anti-depressive agents for depression.The Cochrane database of systematic reviews · 2012Pooled it
- Randomized Controlled Trial of Acceptance and Commitment Therapy for Fatigue Interference With Functioning in Metastatic Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025Trial
- Mindfulness to enhance quality of life and support advance care planning: a pilot randomized controlled trial for adults with advanced cancer and their family caregivers.BMC palliative care · 2024Trial
- Acceptance and commitment therapy for patient fatigue interference and caregiver burden in advanced gastrointestinal cancer: Results of a pilot randomized trial.Palliative medicine · 2022Trial
- Randomized Pilot Trial of a Telephone Symptom Management Intervention for Symptomatic Lung Cancer Patients and Their Family Caregivers.Journal of pain and symptom management · 2016Trial
- The SPADE Symptom Cluster in Primary Care Patients With Chronic Pain.The Clinical journal of pain · 2016Trial
- Longitudinal relationships between fatigue and depression in cancer patients with depression and/or pain.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2013Trial
- Somatic symptoms in cancer patients trajectory over 12 months and impact on functional status and disability.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Trial
- Comparative responsiveness of pain measures in cancer patients.The journal of pain · 2012Trial
- The association of depression and pain with health-related quality of life, disability, and health care use in cancer patients.Journal of pain and symptom management · 2010Trial
- Effect of telecare management on pain and depression in patients with cancer: a randomized trial.JAMA · 2010Trial
- The association of depression and anxiety with health-related quality of life in cancer patients with depression and/or pain.Psycho-oncology · 2010Trial
- Assessing and treating pain in hospices: current state of evidence-based practices.Journal of pain and symptom management · 2010Trial
- Predictors of cancer-related pain improvement over time.Psychosomatic medicineTrial
- Cost effectiveness of telecare management for pain and depression in patients with cancer: results from a randomized trial.General hospital psychiatryTrial
- Patient Health Questionnaire Anxiety and Depression Scale: Initial Validation in Three Clinical Trials.Psychosomatic medicineTrial
- Adverse COVID-19 experiences and physical and psychological outcomes in patients with lung cancer.Palliative & supportive care · 2026Article
- Measurement of patients' acceptable symptom levels and priorities for symptom improvement in advanced prostate cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
objectivePain and depression are two of the most prevalent and treatable cancer-related symptoms, each present in at least 20-30% of oncology patients. Both symptoms are frequently either unrecognized or undertreated, however. This article describes a telecare management intervention delivered by a nurse-psychiatrist team that is designed to improve recognition and treatment of pain and depression. The enrolled sample is also described.
methodsThe Indiana Cancer Pain and Depression study is a National Cancer Institute-sponsored randomized clinical trial. Four hundred five patients with cancer-related pain and/or clinically significant depression from 16 urban or rural oncology practices throughout Indiana have been enrolled and randomized to either the intervention group or to a usual-care control group. Intervention patients receive centralized telecare management coupled with automated home-based symptom monitoring. Outcomes will be assessed at 1, 3, 6 and 12 months by research assistants blinded to treatment arms.
resultsOf 4465 patients screened, 2185 (49%) endorsed symptoms of pain or depression. Of screen-positive patients, about one-third were ineligible (most commonly due to pain or depression not meeting severity thresholds or to pain that is not related to cancer). Of the 405 patients enrolled, 32% have depression only, 24% have pain only and 44% have both depression and pain. At baseline, participants reported an average of 16.8 days out of the past 4 weeks during which they were confined to bed or had to reduce their usual activities by > or =50% due to pain or depression. Also, 176 (44%) reported being unable to work due to health reasons.
conclusionsWhen completed, the Indiana Cancer Pain and Depression trial will test whether centralized telecare management coupled with automated home-based symptom monitoring improves outcomes in cancer patients with depression and/or pain. Findings will be important for both oncologists and mental health clinicians confronted with oncology patients' depression or pain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.