ArticleThe Review of scientific instruments2009
A microcomputed tomography guided fluorescence tomography system for small animal molecular imaging.
Article in The Review of scientific instruments, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 92 citations in OpenAlex.
- Fast ICCD-based temperature modulated fluorescence tomography.Applied optics · 2023Article
- Development of a preclinical CCD-based temperature modulated fluorescence tomography platform.Biomedical optics express · 2022Article
- Nanoliposomes Co-Encapsulating CT Imaging Contrast Agent and Photosensitizer for Enhanced, Imaging Guided Photodynamic Therapy of Cancer.Theranostics · 2019Article
- Optical and x-ray technology synergies enabling diagnostic and therapeutic applications in medicine.Journal of biomedical optics · 2018Review
- Canny edge-based deformable image registration.Physics in medicine and biology · 2017Article
- Simulation-based evaluation of the resolution and quantitative accuracy of temperature-modulated fluorescence tomography.Applied optics · 2015Article
- Macroscopic-imaging technique for subsurface quantification of near-infrared markers during surgery.Journal of biomedical optics · 2015Article
- Micro-CT of rodents: state-of-the-art and future perspectives.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2014Review
- Fast segmentation and high-quality three-dimensional volume mesh creation from medical images for diffuse optical tomography.Journal of biomedical optics · 2013Article
- Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- White light-informed optical properties improve ultrasound-guided fluorescence tomography of photoactive protoporphyrin IX.Journal of biomedical optics · 2013Article
- The effect of temporal impulse response on experimental reduction of photon scatter in time-resolved diffuse optical tomography.Physics in medicine and biology · 2013Article
- Multi-modal molecular diffuse optical tomography system for small animal imaging.Measurement science & technology · 2013Article
- Dual-tracer background subtraction approach for fluorescent molecular tomography.Journal of biomedical optics · 2013Article
- A compact frequency-domain photon migration system for integration into commercial hybrid small animal imaging scanners for fluorescence tomography.Physics in medicine and biology · 2012Article
- In vivo validation of quantitative frequency domain fluorescence tomography.Journal of biomedical optics · 2012Article
- Computed tomography-guided time-domain diffuse fluorescence tomography in small animals for localization of cancer biomarkers.Journal of visualized experiments : JoVE · 2012Article
- Information loss and reconstruction in diffuse fluorescence tomography.Journal of the Optical Society of America. A, Optics, image science, and vision · 2012Article
- Temperature-modulated fluorescence tomography in a turbid media.Applied physics letters · 2012Article
- High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
A prototype small animal imaging system was created for coupling fluorescence tomography (FT) with x-ray microcomputed tomography (microCT). The FT system has the potential to provide synergistic information content resultant from using microCT images as prior spatial information and then allows overlay of the FT image onto the original microCT image. The FT system was designed to use single photon counting to provide maximal sensitivity measurements in a noncontact geometry. Five parallel detector locations are used, each allowing simultaneous sampling of the fluorescence and transmitted excitation signals through the tissue. The calibration and linearity range performance of the system are outlined in a series of basic performance tests and phantom studies. The ability to image protoporphyrin IX in mouse phantoms was assessed and the system is ready for in vivo use to study biological production of this endogenous marker of tumors. This multimodality imaging system will have a wide range of applications in preclinical cancer research ranging from studies of the tumor microenvironment and treatment efficacy for emerging cancer therapeutics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.