Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2010
Marine phospholipids--a promising new dietary approach to tumor-associated weight loss.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Pharmacological management of cachexia in adult cancer patients: a systematic review of clinical trials.BMC cancer · 2018Pooled it
- A systematic review of health-related quality of life instruments in patients with cancer cachexia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Pooled it
- The effects of EPA and DHA enriched fish oil on nutritional and immunological markers of treatment naïve breast cancer patients: a randomized double-blind controlled trial.Nutrition journal · 2017Trial
- Dietary supplementation with n-3-fatty acids in patients with pancreatic cancer and cachexia: marine phospholipids versus fish oil - a randomized controlled double-blind trial.Lipids in health and disease · 2017Trial
- Understanding the Role of Polyunsaturated Fatty Acids in the Development and Prevention of Cancer.Cancer treatment and research · 2024Review
- A Review of Nutraceuticals in Cancer Cachexia.Cancers · 2023Review
- Positional Distribution of Fatty Acids in Processed Chinook Salmon Roe Lipids Determined byMolecules (Basel, Switzerland) · 2023Article
- Dietary Supplements in People with Metastatic Cancer Who Are Experiencing Malnutrition, Cachexia, Sarcopenia, and Frailty: A Scoping Review.Nutrients · 2022Article
- Critical Review on Fatty Acid-Based Food and Nutraceuticals as Supporting Therapy in Cancer.International journal of molecular sciences · 2022Review
- Cardio-Protective Properties and Health Benefits of Fish Lipid Bioactives; The Effects of Thermal Processing.Marine drugs · 2022Review
- Diet-related interventions for cancer-associated cachexia.Journal of cancer research and clinical oncology · 2021Review
- Pancreatic Cancer Cachexia: The Role of Nutritional Interventions.Healthcare (Basel, Switzerland) · 2019Review
- The Potential Role of Dietary Platelet-Activating Factor Inhibitors in Cancer Prevention and Treatment.Advances in nutrition (Bethesda, Md.) · 2019Review
- Article
- Sophora flavescens Containing-QYJD Formula Activates Nrf2 Anti-Oxidant Response, Blocks Cellular Transformation and Protects Against DSS-Induced Colitis in Mouse Model.The American journal of Chinese medicine · 2018Article
- [Importance of long chain omega-3 fatty acids in prostate cancer].Der Urologe. Ausg. A · 2014Review
- Effects of Marine Phospholipids Extract on the Lipid Levels of Metastatic and Nonmetastatic Prostate Cancer Patients.International scholarly research notices · 2014Article
- Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model.International journal of oncology · 2013Article
- Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism.Oncology letters · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
goals of workAdvanced tumor disease very often evokes excessive loss of body weight. Among others, fish oil or marine fatty acid ethyl esters were investigated for treatment of cancer cachexia with controversial results. In this study, a new formulation of marine fatty acids was investigated, the marine phospholipids, with more than 50% of phospholipid-bound fatty acids being eicosapentaenoic and docosahexaenoic acid. MATERIALS AND
methodsThirty-one tumor patients with various tumor entities suffering from weight loss were asked to take marine phospholipids (1.5 g/day) as softgel capsules for a period of 6 weeks. Compliance, body weight, appetite, and quality of life as well as the fatty acid profile in plasma and blood cells were monitored; 17 patients could be analyzed. MAIN
resultsMarine phospholipids were very well accepted; low-dose supplementation resulted in a significant increase of eicosapentaenoic and docosahexaenoic acid in plasma phospholipids; therefore, significantly reducing the n-6 to n-3 fatty acid ratio. A stabilization of body weight was achieved (median weight change of +0.6% after 6 weeks), while appetite and quality of life improved.
conclusionsThese promising first results encourage further investigation of marine phospholipids in cancer care.
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