ArticleImmunogenetics2009
Origin and evolution of the vertebrate leukocyte receptors: the lesson from tunicates.
Article in Immunogenetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Understanding vertebrate immunity through comparative immunology.Nature reviews. Immunology · 2025Review
- Genomic view of the origins of cell-mediated immunity.Immunogenetics · 2023Article
- An Ancient MHC-Linked Gene Encodes a Nonrearranging Shark Antibody, UrIg, Convergent with IgG.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis.Developmental and comparative immunology · 2015Article
- Immune-directed support of rich microbial communities in the gut has ancient roots.Developmental and comparative immunology · 2014Review
- Article
- Chicken CRTAM binds nectin-like 2 ligand and is upregulated on CD8+ αβ and γδ T lymphocytes with different kinetics.PloS one · 2013Article
- Evolution of the B7 family: co-evolution of B7H6 and NKp30, identification of a new B7 family member, B7H7, and of B7's historical relationship with the MHC.Immunogenetics · 2012Article
- Identification of a chicken CLEC-2 homologue, an activating C-type lectin expressed by thrombocytes.Immunogenetics · 2012Article
- A Basal chordate model for studies of gut microbial immune interactions.Frontiers in immunology · 2012Article
- A role for variable region-containing chitin-binding proteins (VCBPs) in host gut-bacteria interactions.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- The invention of lymphocytes.Current opinion in immunology · 2011Review
- Hydractinia allodeterminant alr1 resides in an immunoglobulin superfamily-like gene complex.Current biology : CB · 2010Article
- Fish 'n' TRIMs.Journal of biology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two selected receptor genes of the immunoglobulin superfamily (IgSF), one CTX/JAM family member, and one poliovirus receptor-like nectin that have features of adhesion molecules can be expressed by Ciona hemocytes, the effectors of immunity. They can also be expressed in the nervous system (CTX/JAM) and in the ovary (nectin). The genes encoding these receptors are located among one set of genes, spread over Ciona chromosomes 4 and 10, and containing other IgSF members homologous to those encoded by genes present in a tetrad of human (1, 3 + X, 11, 21 + 19q) or bird chromosomes (1, 4, 24, 31) that include the leukocyte receptor complex. It is proposed that this tetrad is due to the two rounds of duplication that affected a single prevertebrate ancestral region containing a primordial leukocyte receptor complex involved in immunity and other developmental regulatory functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.