ArticleHFSP journal2007
How single molecule detection measures the dynamic actions of life.
Article in HFSP journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Denoise Stepwise Signals by Diffusion Model-Based Approach.Small methods · 2026Article
- Measuring molecular motor forces in vivo: implications for tug-of-war models of bidirectional transport.Biophysical journal · 2012Article
- Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study.The Journal of cell biology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomolecules dynamically work in cells in which a variety of molecules assemble and interact in unique manner. The molecular mechanisms underlying several biological processes have been elucidated from the results obtained from the descriptions of cell function, from the snapshots of the structures of biomolecules involved in these processes, and from the biochemical properties of these reactions in vitro. Recently developed single molecule measurements have revealed the dynamic properties of the biomolecules that have been hidden in the data that have been averaged over large numbers of molecules in both ensemble measurement and in cells. Single molecule imaging and manipulation of single molecules have allowed the visualization of the dynamic operations of molecular motors, enzymatic reactions, structural dynamics of biomolecules, and cell signaling processes. The results have shown that the single molecule techniques are powerful tools to monitor the dynamic actions of biomolecules and their assemblies. This approach has been applied to a variety of fields within the life sciences. As new information emerges about the dynamic actions of biomolecules using methods of single molecule detection new views on how biological processes work will be revealed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.