ArticleHFSP journal2008
Pulsing cells: how fast is too fast?
Article in HFSP journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability.eLife · 2024Article
- Band-pass processing in a GPCR signaling pathway selects for NFAT transcription factor activation.Integrative biology : quantitative biosciences from nano to macro · 2015Article
- How to train your microbe: methods for dynamically characterizing gene networks.Current opinion in microbiology · 2015Review
- Adaptive molecular networks controlling chemotactic migration: dynamic inputs and selection of the network architecture.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- The Dynamical Systems Properties of the HOG Signaling Cascade.Journal of signal transduction · 2011Article
- Oscillatory signaling processes: the how, the why and the where.Current opinion in genetics & development · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Signal transduction pathways are complex coupled sets of biochemical reactions evolved to transmit and process information about the state of the immediate cell environment. Can we design experiments that would inform us about the properties and limitations of signal processing? Recent studies suggest that this indeed can be achieved by exciting a cell with carefully designed oscillatory stimuli. Although this analysis has its caveats, complex temporal stimulation of signal transduction networks can serve to rapidly advance our understanding of these information channels and ultimately create intelligent ways of controlling them.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.