SynthesisJournal of medical Internet research2009
Adherence in internet interventions for anxiety and depression.
Synthesis in Journal of medical Internet research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04948996 (Effectiveness of Group Versus Individual Self-management of Depression Using a Mobile App to Increase Treatment Adherence Among Users of a University-based Helpline in the Dominican Republic.), which is not on this map. Cited by 621 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Group Versus Individual Self-management of Depression Using a Mobile App to Increase Treatment Adherence Among Users of a University-based Helpline in the Dominican Republic.
Who cites it
621 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Understanding Adherence to Digital Health Technologies: Systematic Review of Predictive Factors.Journal of medical Internet research · 2025Pooled it
- The effectiveness of mindfulness-based cognitive therapy on rumination and related psychological indicators: a systematic review and meta-analysis.BMC psychology · 2025Pooled it
- Internet- and mobile-based anxiety and depression interventions for children and adolescents: efficacy and negative effects - a systematic review and meta-analysis.European child & adolescent psychiatry · 2025Pooled it
- Factors Associated With Digital Intervention Engagement and Adherence in Patients With Cancer: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Efficacy of psychosocial interventions to reduce affective symptoms in sexual and gender minorities: a systematic review and meta-analysis of randomized controlled trials.BMC psychiatry · 2024Pooled it
- Assessing Patient Adherence to and Engagement With Digital Interventions for Depression in Clinical Trials: Systematic Literature Review.Journal of medical Internet research · 2023Pooled it
- Skill Enactment and Knowledge Acquisition in Digital Cognitive Behavioral Therapy for Depression and Anxiety: Systematic Review of Randomized Controlled Trials.Journal of medical Internet research · 2023Pooled it
- Remote cognitive-behavioral therapy for generalized anxiety disorder: A preliminary meta-analysis.Journal of clinical psychology · 2022Pooled it
- Online psychosocial interventions for improving mental health in people during the COVID-19 pandemic: A systematic review and meta-analysis.Journal of affective disorders · 2022Pooled it
- The Effects of Nonclinician Guidance on Effectiveness and Process Outcomes in Digital Mental Health Interventions: Systematic Review and Meta-analysis.Journal of medical Internet research · 2022Pooled it
- A Smartphone-Based Ecological Momentary Intervention for Workplace Mental Health: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Population-based RCT of a digital cognitive-behavioural guided self-help intervention for anxiety, depression and eating disorders in college students.Nature human behaviour · 2026Trial
- Trial
- Adherence, Acceptability, and Sexual Health Outcomes of the Odeya App-Based Intervention for Sexual Distress in Women With Endometriosis: Randomized Controlled Mixed Methods Trial.Journal of medical Internet research · 2026Trial
- Evaluating User Engagement and Satisfaction With Digital Mental Health Interventions: Randomized Controlled Trial of a Text Messaging Program and e-Mental Health Resources.JMIR human factors · 2026Trial
- A two-armed pragmatic randomized controlled trial comparing the effectiveness of two self-compassion interventions at reducing perceived stress.Frontiers in digital health · 2026Trial
- An App-Based Cognitive Behavioral Therapy Program Tailored for College Students: Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- Effect of a web-based intervention on the mental health of informal caregivers of the elderly: a randomized controlled trial.BMC psychiatry · 2025Trial
- Effectiveness of an Internet-Based, Self-Guided, Short-Term Mindfulness Training (ISSMT) Program for Relieving Depressive Symptoms in the Adult Population in China: Single-Blind, Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Studying the Digital Intervention Engagement-Mediated Relationship Between Intrapersonal Measures and Pre-Exposure Prophylaxis Adherence in Sexual and Gender Minority Youth: Secondary Analysis of a Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
561 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOpen access websites which deliver cognitive and behavioral interventions for anxiety and depression are characterised by poor adherence. We need to understand more about adherence in order to maximize the impact of Internet-based interventions on the disease burden associated with common mental disorders.
objectiveThe aims of this paper are to review briefly the adherence literature with respect to Internet interventions and to investigate the rates of dropout and compliance in randomized controlled trials of anxiety and depression Web studies.
methodsA systematic review of randomized controlled trials using Internet interventions for anxiety and depression was conducted, and data was collected on dropout and adherence, predictors of adherence, and reasons for dropout.
resultsRelative to reported rates of dropout from open access sites, the present study found that the rates of attrition in randomized controlled trials were lower, ranging from approximately 1 - 50%. Predictors of adherence included disease severity, treatment length, and chronicity. Very few studies formally examined reasons for dropout, and most studies failed to use appropriate statistical techniques to analyze missing data.
conclusionsDropout rates from randomized controlled trials of Web interventions are low relative to dropout from open access websites. The development of theoretical models of adherence is as important in the area of Internet intervention research as it is in the behavioral health literature. Disease-based factors in anxiety and depression need further investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.