ArticleEmerging infectious diseases2009
CTX-M beta-lactamases in Escherichia coli from community-acquired urinary tract infections, Cambodia.
Article in Emerging infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 115 citations in OpenAlex.
- Evaluating extraction-free PCR for rapid detection of beta-lactam antibiotic resistance in urinary tract infection.Practical laboratory medicine · 2026Article
- Prevalence and characterization of third-generation cephalosporin, carbapenem and colistin-resistant Enterobacterales isolated from clinical samples in Cambodia.New microbes and new infections · 2025Article
- Molecular characterization of antimicrobial resistance genes and plasmid profiles in enterobacterales isolated from urinary tract infections in rural outpatient women in Otavalo, Ecuador.BMC infectious diseases · 2025Article
- Bacterial Genomics for National Antimicrobial Resistance Surveillance in Cambodia.The Journal of infectious diseases · 2025Article
- Comprehensive Genomic Analysis of UropathogenicPathogens (Basel, Switzerland) · 2024Article
- Characterization of beta-lactamase producingIranian journal of microbiology · 2023Article
- Comparative Genetic Characterization of CTX-M-ProducingMicroorganisms · 2023Article
- Surveillance and prevalence of antimicrobial resistant bacteria from public settings within urban built environments: Challenges and opportunities for hygiene and infection control.Environment international · 2021Review
- Anti-biofilm and anti-virulence effects of silica oxide nanoparticle-conjugation of lectin purified from Pseudomonas aeruginosa.IET nanobiotechnology · 2021Article
- Epidemiology of Extended-Spectrum Beta-Lactamase and Carbapenemase-Producing Enterobacterales in the Greater Mekong Subregion: A Systematic-Review and Meta-Analysis of Risk Factors Associated With Extended-Spectrum Beta-Lactamase and Carbapenemase Isolation.Frontiers in microbiology · 2021Review
- Markers Specific toInternational journal of environmental research and public health · 2020Article
- A Lateral Flow Immunoassay for the Rapid Identification of CTX-M-Producing Enterobacterales from Culture Plates and Positive Blood Cultures.Diagnostics (Basel, Switzerland) · 2020Article
- Third-generation cephalosporin-resistant urinary tract infections in children presenting to the paediatric emergency department.Paediatrics & child health · 2020Article
- Novel determination ofNew microbes and new infections · 2020Article
- Detection ofIranian journal of microbiology · 2019Article
- Epidemiology of paediatric gastrointestinal colonisation by extended spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates in north-west Cambodia.BMC microbiology · 2019Article
- Study of class 1 integrons in multidrug-resistant uropathogenicIranian journal of basic medical sciences · 2018Article
- Molecular Epidemiology of Dairy Cattle-Associated Escherichia coli CarryingApplied and environmental microbiology · 2018Article
- Molecular characterization ofNew microbes and new infections · 2018Article
- Detection of ctx-M gene in ESBL-producing E. coli strains isolated from urinary tract infection in Semnan, Iran.Electronic physician · 2016Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the recent global spread of CTX-M beta-lactamases in Escherichia coli isolates from community-acquired urinary tract infections (CA-UTIs), their dissemination has been little studied in developing countries. In a 2-year prospective study, we documented the prevalence of extended-spectrum beta-lactamases (ESBLs) in E. coli that were responsible for CA-UTIs in Phnom-Penh, Cambodia. Ninety-three E. coli strains were included. We observed a high prevalence of resistance to amoxicillin (88.2% of strains), cotrimoxazole (75.3%), ciprofloxacin (67.7%), gentamicin (42.5%), and third-generation cephalosporins (37.7%). A total of 34 strains carried ESBLs, all of which were CTX-M type. CTX-M carriage was associated with resistance to fluoroquinolones and aminoglycosides. U using repetitive extragenic palindromic-PCR, we identified 4 clusters containing 9, 8, 3, and 2 strains. The prevalence of CTX-M beta-lactamases has reached a critical level in Cambodia, which highlights the need for study of their spread in developing countries.
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Registered trials
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