ArticleBMC genomics2009
Genome wide expression analysis of CBS domain containing proteins in Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their developmental and stress regulation.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
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Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.
- Meta-analysis, WGCNA, and machine learning converge on a four-gene biomarker panel for heat stress tolerance in Solanum lycopersicum.Scientific reports · 2026Pooled it
- Genetic Variation and Genome-Enabled Prediction of White Lupin Frost Resistance in Different Reference Populations.International journal of molecular sciences · 2025Article
- Analysis of Growth Trajectories and Verification of Related SNPs inInternational journal of molecular sciences · 2023Article
- GWAS and Meta-QTL Analysis of Yield-Related Ear Traits in Maize.Plants (Basel, Switzerland) · 2023Article
- CBSX2 is required for the efficient oxidation of chloroplast redox-regulated enzymes in darkness.Plant direct · 2023Article
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- The transcribed centromeric gene OsMRPL15 is essential for pollen development in rice.Plant physiology · 2023Article
- RNA-seq analysis and reconstruction of gene networks involved in response to salinity stress in quinoa (cv. Titicaca).Scientific reports · 2023Article
- Genomic Survey of Flavin Monooxygenases in Wild and Cultivated Rice Provides Insight into Evolution and Functional Diversities.International journal of molecular sciences · 2023Article
- Physiological and Transcriptional Responses ofInternational journal of molecular sciences · 2023Article
- Engineering drought and salinity tolerance traits in crops through CRISPR-mediated genome editing: Targets, tools, challenges, and perspectives.Plant communications · 2022Review
- An Overview of Pentatricopeptide Repeat (PPR) Proteins in the MossPlants (Basel, Switzerland) · 2022Review
- Identification of quantitative trait loci for tillering, root, and shoot biomass at the maximum tillering stage in rice.Scientific reports · 2022Article
- Adenylates regulate Arabidopsis plastidial thioredoxin activities through the binding of a CBS domain protein.Plant physiology · 2022Article
- Genetic Conservation of CBS Domain Containing Protein Family inInternational journal of molecular sciences · 2022Article
- Genome-wide characterization of cys-tathionine-β-synthase domain-containing proteins in sugarcane reveals their role in defense responses under multiple stressors.Frontiers in plant science · 2022Article
- Genome-wide identification of cystathionine beta synthase genes in wheat and its relationship with anther male sterility under heat stress.Frontiers in plant science · 2022Article
- A genome variation map provides insights into the genetics of walnut adaptation and agronomic traits.Genome biology · 2021Article
- Genome-Wide Investigation and Expression Profiling Under Abiotic Stresses of a Soybean Unknown Function (DUF21) and Cystathionine-β-Synthase (CBS) Domain-Containing Protein Family.Biochemical genetics · 2021Article
- Bruchid beetle ovipositioning mediated defense responses in black gram pods.BMC plant biology · 2021Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Arabidopsis thaliana (L.) Heynh and Oryza sativa L., a large number of genes encode proteins of unknown functions, whose characterization still remains one of the major challenges. With an aim to characterize these unknown proteins having defined features (PDFs) in plants, we have chosen to work on proteins having a cystathionine beta-synthase (CBS) domain. CBS domain as such has no defined function(s) but plays a regulatory role for many enzymes and thus helps in maintaining the intracellular redox balance. Its function as sensor of cellular energy has also been widely suggested.
resultsOur analysis has identified 34 CBS domain containing proteins (CDCPs) in Arabidopsis and 59 in Oryza. In most of these proteins, CBS domain coexists with other functional domain(s), which may indicate towards their probable functions. In order to investigate the role(s) of these CDCPs, we have carried out their detailed analysis in whole genomes of Arabidopsis and Oryza, including their classification, nomenclature, sequence analysis, domain analysis, chromosomal locations, phylogenetic relationships and their expression patterns using public databases (MPSS database and microarray data). We have found that the transcript levels of some members of this family are altered in response to various stresses such as salinity, drought, cold, high temperature, UV, wounding and genotoxic stress, in both root and shoot tissues. This data would be helpful in exploring the so far obscure functions of CBS domain and CBS domain-containing proteins in plant stress responses.
conclusionWe have identified, classified and suggested the nomenclature of CDCPs in Arabidopsis and Oryza. A comprehensive analysis of expression patterns for CDCPs using the already existing transcriptome profiles and MPSS database reveals that a few CDCPs may have an important role in stress response/tolerance and development in plants, which needs to be validated further through functional genomics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.