Evidence map›Paper›PMID 19400868›Full record

ReviewAPMIS : acta pathologica, microbiologica, et immunologica Scandinavica2009

Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence.

Ira J Blader, Jeroen P Saeij

Open access · greenAbstract readReview
In one paragraph

Review in APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 45 citations in OpenAlex.

  1. A review onParasite epidemiology and control · 2026
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  6. The proteomic landscape ofFrontiers in cellular and infection microbiology · 2025
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  13. Identification ofmSphere · 2023
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  14. Histone variant H2B.Z acetylation is necessary for maintenance ofbioRxiv : the preprint server for biology · 2023
    Article
  15. Article
  16. The Impact of LatentMicroorganisms · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ira J BladerDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. iblader@ouhsc.edu
Jeroen P Saeij
Massachusetts Institute of Technology · USUniversity of Oklahoma Health Sciences Center · US

Funding

CONTROL OF TOXOPLASMA GONDII GROWTH BY THE HOST CELL TRANSCRIPTION FACTOR HIF1R01AI069986 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI BLADER, IRA J · 2006 to 2021
$5.7M
NIAID NIH HHS R01 AI069986NIAID NIH HHS R01AI069986
6 · The paper itself

Abstract

Toxoplasma gondii is an obligate intracellular protozoan parasite that can infect most warm-blooded animals and cause severe and life-threatening disease in developing fetuses and in immune-compromised patients. Although Toxoplasma was discovered over 100 years ago, we are only now beginning to appreciate the importance of the role that parasite modulation of its host has on parasite growth, bradyzoite development, immune evasion, and virulence. The goal of this review is to highlight these findings, to develop an integrated model for communication between Toxoplasma and its host, and to discuss new questions that arise out of these studies.

Indexed as

Host-Parasite InteractionsAnimalsCell AdhesionCell CycleCytokinesCytoskeletonDisease ProgressionGene Expression RegulationGenotypeHumansMiceOrganellesProtozoan ProteinsToxoplasmaToxoplasmosisToxoplasmosis, AnimalCytokinesProtozoan Proteins

Identifiers

PMID19400868
PMCPMC2810527
OpenAlexW1514340100

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.