ReviewAnnual review of neuroscience2009
Synaptic mechanisms for plasticity in neocortex.
Review in Annual review of neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 326 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
326 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy of tailor-made notched music training (TMNMT) in the treatment of tinnitus: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Pooled it
- Immediate and long-term efficacy of transcranial direct current stimulation (tCDS) in obsessive-compulsive disorder, posttraumatic stress disorder and anxiety disorders: a systematic review and meta-analysis.Translational psychiatry · 2024Pooled it
- Outcomes and clinical implications of intranasal insulin on cognition in humans: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Multi-networks connectivity at baseline predicts the clinical efficacy of left angular gyrus-navigated rTMS in the spectrum of Alzheimer's disease: A sham-controlled study.CNS neuroscience & therapeutics · 2023Trial
- A randomized, placebo-controlled laboratory study of the effects of D-cycloserine on sexual memory consolidation in women.Psychopharmacology · 2020Trial
- Effects of Augmenting N-Methyl-D-Aspartate Receptor Signaling on Working Memory and Experience-Dependent Plasticity in Schizophrenia: An Exploratory Study Using Acute d-cycloserine.Schizophrenia bulletin · 2017Trial
- Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain.Proceedings of the National Academy of Sciences of the United States of America · 2015Trial
- Schizophrenia: from mechanism to therapy.Science China. Life sciences · 2026Review
- Modeling homosynaptic and heterosynaptic plasticity with a single neuromemristive synapse.Journal of advanced research · 2026Article
- Global remapping of the sensory homunculus emerges early in childhood development.Nature communications · 2026Article
- Visual experience drives functional reorganization of cortical GABAergic circuits.bioRxiv : the preprint server for biology · 2026Article
- Continuous partitioning of neuronal variability.bioRxiv : the preprint server for biology · 2025Article
- Article
- Review
- Voluntary running improves synaptic degeneration of the anterior cingulate cortex in knee osteoarthritis.Molecular brain · 2025Article
- Closed-Loop Connectivity Best Supports Angular Tuning and Sleep Dynamics in a Biophysical Thalamocortical Circuit Model.bioRxiv : the preprint server for biology · 2025Article
- Molecular states underlying neuronal cell type development and plasticity in the postnatal whisker cortex.PLoS biology · 2025Article
- The Role of Complexity Theory in Understanding Brain's Neuron-Glia Interactions.The European journal of neuroscience · 2025Review
- Level of M1 GABAB predicts micro offline consolidation of motor learning during wakefulness.NPJ science of learning · 2025Article
- Repetitive Sensory Stimulation Potentiates and Recruits Sensory-Evoked Cortical Population Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
266 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Sensory experience and learning alter sensory representations in cerebral cortex. The synaptic mechanisms underlying sensory cortical plasticity have long been sought. Recent work indicates that long-term cortical plasticity is a complex, multicomponent process involving multiple synaptic and cellular mechanisms. Sensory use, disuse, and training drive long-term potentiation and depression (LTP and LTD), homeostatic synaptic plasticity and plasticity of intrinsic excitability, and structural changes including formation, removal, and morphological remodeling of cortical synapses and dendritic spines. Both excitatory and inhibitory circuits are strongly regulated by experience. This review summarizes these findings and proposes that these mechanisms map onto specific functional components of plasticity, which occur in common across the primary somatosensory, visual, and auditory cortices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.