ReviewJournal of cancer research and clinical oncology2009
Experimental models of hepatocellular carcinoma: developments and evolution.
Review in Journal of cancer research and clinical oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Pharmacokinetic herb-drug interactions between Aidi injection and doxorubicin in rats with diethylnitrosamine-induced hepatocellular carcinoma.BMC pharmacology & toxicology · 2021Article
- Study on the hepatocellular carcinoma model with metastasis.Genes & diseases · 2020Review
- Article
- A Nude Mouse Model of Orthotopic Liver Transplantation of Human Hepatocellular Carcinoma HCCLM3 Cell Xenografts and the Use of Imaging to Evaluate Tumor Progression.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Establishment of a dual-color fluorescence tracing orthotopic transplantation model of hepatocellular carcinoma.Molecular medicine reports · 2016Article
- Chemosensitization of HepG2 cells by suppression of NF-κB/p65 gene transcription with specific-siRNA.World journal of gastroenterology · 2015Article
- Establishment of experimental implantation tumor models of hepatocellular carcinoma in Wistar rats.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- Establishment of NOD/SCID mouse models of human hepatocellular carcinoma via subcutaneous transplantation of histologically intact tumor tissue.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2013Article
- Establishment of an orthotopic transplantation tumor model of hepatocellular carcinoma in mice.World journal of gastroenterology · 2012Article
- Intratumoral versus intravenous gene therapy using a transcriptionally targeted viral vector in an orthotopic hepatocellular carcinoma rat model.Journal of vascular and interventional radiology : JVIR · 2012Article
- Gadoxetate acid-enhanced MRI of hepatocellular carcinoma in a c-myc/TGFα transgenic mouse model including signal intensity and fat content: initial experience.Cancer imaging : the official publication of the International Cancer Imaging Society · 2012Article
- Hepatocellular carcinoma: insight from animal models.Nature reviews. Gastroenterology & hepatology · 2011Review
- Liver engraftment potential of hepatic cells derived from patient-specific induced pluripotent stem cells.Cell cycle (Georgetown, Tex.) · 2011Article
- Chitosan-alginate scaffold culture system for hepatocellular carcinoma increases malignancy and drug resistance.Pharmaceutical research · 2010Article
- Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis.Pharmaceutical research · 2010Article
- Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by proteomics analysis and clinical validation.Journal of experimental & clinical cancer research : CR · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. The biological mechanisms of hepatocarcinogenesis and progression are poorly understood. Experimental models of HCC provide valuable tools to evaluate the risk factors, new treatment modalities and biologic characteristics. Under the constant evolution in model design and technology development, new experimental models continue to emerge, including spontaneous models, induced models, viral models, transplantable models, and genetically engineered models. These models are used as tools to investigate basic biological mechanisms of growth and differentiation, oncogene function, and as systems to test new diagnostic and therapeutic approaches. Each model has its own advantages and disadvantages. The progress in HCC model construction and studies are summarized in this review.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.