Evidence map›Paper›PMID 19399437›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2009

Multicell simulations of development and disease using the CompuCell3D simulation environment.

Maciej H Swat, Susan D Hester, Ariel I Balter, Randy W Heiland, Benjamin L Zaitlen, James A Glazier

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Comparative analysis of continuum angiogenesis models.Journal of mathematical biology · 2021
    Article
  7. Software for Bioprinting.International journal of bioprinting · 2020
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The importance of geometry in mathematical models of developing systems.Current opinion in genetics & development · 2012
    Review
  17. Article
  18. Article
  19. Modeling cellular processes in 3D.Trends in cell biology · 2011
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maciej H SwatBiocomplexity Institute and Department of Physics, Indiana University, Bloomington, USA.
Susan D Hester
Ariel I Balter
Randy W Heiland
Benjamin L Zaitlen
James A Glazier

Funding

MSM - Multiscale Studies of Segmentation in Vertebrate *R01GM076692 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI GLAZIER, JAMES ALEXANDER, STERN, CLAUDIO D · 2005 to 2015
$5.5M
Development and Improvement of Tissue Simulation ToolkitR01GM077138 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI D'SOUZA, ROSHAN M, GLAZIER, JAMES ALEXANDER · 2007 to 2015
$4.0M
NIGMS NIH HHS 1R01 GM076692-01NIGMS NIH HHS 1R01 GM077138-01A1NIGMS NIH HHS R01 GM076692NIGMS NIH HHS R01 GM077138
6 · The paper itself

Abstract

Mathematical modeling and computer simulation have become crucial to biological fields from genomics to ecology. However, multicell, tissue-level simulations of development and disease have lagged behind other areas because they are mathematically more complex and lack easy-to-use software tools that allow building and running in silico experiments without requiring in-depth knowledge of programming. This tutorial introduces Glazier-Graner-Hogeweg (GGH) multicell simulations and CompuCell3D, a simulation framework that allows users to build, test, and run GGH simulations.

Indexed as

Computer SimulationDevelopmental BiologyDiseaseAlgorithmsAnimalsHumansImaging, Three-DimensionalMathematicsModels, TheoreticalProgramming LanguagesSoftware

Identifiers

PMID19399437
PMCPMC2739628

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.