ArticleJournal of Korean medical science2009
The impact of smoking on clinical and therapeutic effects in asthmatics.
Article in Journal of Korean medical science, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Tobacco and asthma: presenting the world health organization (WHO) tobacco knowledge summary.Substance abuse treatment, prevention, and policy · 2025Review
- Relationships Between High-Resolution Computed Tomographic Features and Lung Function Trajectory in Patients With Asthma.Allergy, asthma & immunology research · 2023Article
- Asthma and Tobacco Smoking.Journal of personalized medicine · 2022Review
- The Impact of Tobacco Smoking on Adult Asthma Outcomes.International journal of environmental research and public health · 2021Article
- Modelling the asthma phenotype: impact of cigarette smoke exposure.Respiratory research · 2018Article
- Proteomic identification of moesin upon exposure to acrolein.Proteome science · 2018Article
- Analysis of Plasma Concentrations of Theophylline in Smoking and Nonsmoking Patients with Asthma.Open access Macedonian journal of medical sciences · 2015Article
- Physician-prescribed Asthma Treatment Regimen does not differ Between Smoking and Non-smoking Patients With Asthma in Seoul and Gyunggi province of Korea.Allergy, asthma & immunology research · 2015Article
- Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization.Metallomics : integrated biometal science · 2011Review
- Effects of smoking cessation on airflow obstruction and quality of life in asthmatic smokers.Allergy, asthma & immunology research · 2010Article
- Clinical characteristics of adult asthma.Allergy, asthma & immunology research · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smoking is associated with poor symptom control and impaired therapeutic responses in asthma. A total of 843 patients with asthma were recruited. The patients received treatment for 1 yr according to the severity of their asthma. We compared the forced expiratory volume in 1 sec (FEV1), the ratio of FEV1 to forced vital capaity (FVC), atopy, total IgE, emphysema on high-resolution computed tomography (HRCT), the number of near-fatal asthma attacks, and physiological fixed airway obstruction between the smoking and nonsmoking groups. The study population consisted of 159 (18.8%) current smokers, 157 (18.7%) ex-smokers, and 525 (62.5%) nonsmokers. Although the prevalence of atopy was not different between the smoking and nonsmoking groups, the total IgE was higher among the smokers than the nonsmokers. Compared with the nonsmoking group, the smokers had a lower FEV1 % predicted and forced expiratory flow between 25 and 75% of FVC. A greater prevalence of emphysema and a significantly higher number of asthmatic patients with fixed airway obstruction were detected in the smoking versus nonsmoking group. The 37.5% of asthmatic patients who were former or current smokers showed decreased pulmonary function and increased IgE, emphysema on HRCT, and fixed airway obstruction, indicating that smoking can modulate the clinical and therapeutic responses in asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.