Evidence map›Paper›PMID 19399010›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2009

Support of the preterm circulation: keynote address to the Fifth Evidence vs Experience Conference, Chicago, June 2008.

N Evans

Abstract readAddressCase Reports
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

N EvansDepartment of Newborn Care, Royal Prince Alfred Hospital and University of Sydney, Sydney, NSW, Australia. nevans@med.usyd.edu.au

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodynamics is an area of neonatology that is marked more by what we do not know than what we do. What is clear is that it is much more complex than just measuring blood pressure (BP). Early postnatal preterm hemodynamic pathophysiology is characterized by low systemic blood flow (SBF), possibly relating to a mix of afterload compromise, left-to-right shunting through the unconstricted ductus and to the circulatory effects of ventilation. After approximately 24 h of age, vasodilatation seems to be the dominant pathology. In the face of this complexity, a one-size-fits-all approach to treatment that will be applicable in a large clinical trial may prove elusive. The possibility of using a measure of both BP and SBF to target an appropriate treatment needs to be explored.

Indexed as

Evidence-Based MedicineBlood Flow VelocityBlood PressureBrain IschemiaCardiac Output, LowCardiotonic AgentsCombined Modality TherapyDobutamineDopamineDuctus Arteriosus, PatentHemodynamicsHomeostasisHumansInfant, NewbornInfant, Premature, DiseasesIntensive Care, NeonatalCardiotonic AgentsDobutamineDopamine

Identifiers

PMID19399010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.