ReviewJournal of perinatology : official journal of the California Perinatal Association2009
Relative adrenal insufficiency in the preterm and term infant.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 157 citations in OpenAlex.
- Trial
- Complex Glycerol Kinase Deficiency: A Case of Segmental Loss of Xp Chromosome - Correspondence.Indian journal of pediatrics · 2026Article
- Nutritional management at 22-23 weeks gestational age: evidence and knowledge gaps.Pediatric research · 2026Review
- Systemic glucocorticoid activity in extremely preterm neonates after antenatal betamethasone and intratracheal budesonide: a sub-study of the PLUSS trial.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Glucocorticoid trajectories in preterm infants-born too soon, wired differently.The Journal of clinical endocrinology and metabolism · 2026Article
- Management of Hypoxemic Respiratory Failure in the Newborn During Therapeutic Hypothermia.Clinics in perinatology · 2026Review
- Recurrent Hypoglycemia in Two Late-Preterm Infants With Transitional Disorder of Glucose Mobilization-Case Series.Clinical case reports · 2026Article
- Stress exposure, stress responses, and short-term outcomes in very preterm neonates: a national cohort study.European journal of pediatrics · 2026Observational
- Elevation of corticosterone and 17OH progesterone in extremely preterm infants and clinical implications.Pediatric research · 2026Article
- Use of hydrocortisone in extremely preterm infants: emphasis on those born least mature.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- Perinatal glucocorticoid sensitivity in the preterm newborn: molecular mechanisms, endogenous determinants, and clinical implications.Frontiers in endocrinology · 2025Review
- An Update on Pharmacologic Management of Neonatal Hypotension: When, Why, and Which Medication.Children (Basel, Switzerland) · 2024Review
- Steroid Metabolomic Signature in Term and Preterm Infants.Biomolecules · 2024Article
- Impact of postnatal steroids on peripheral avascular retina and severity of retinopathy of prematurity.Pediatric research · 2023Article
- Evaluation of cross-platform compatibility of a DNA methylation-based glucocorticoid response biomarker.Clinical epigenetics · 2022Article
- Presumed adrenal insufficiency in neonates treated with corticosteroids for the prevention of bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Hemodynamic dysfunction in neonatal sepsis.Pediatric research · 2022Review
- Life-threatening PPHN refractory to nitric oxide: proposal for a rational therapeutic algorithm.European journal of pediatrics · 2021Review
- Management of systemic hypotension in term infants with persistent pulmonary hypertension of the newborn: an illustrated review.Archives of disease in childhood. Fetal and neonatal edition · 2021Review
- Clinical risk factors for the development of late-onset circulatory collapse in premature infants.Pediatric research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cortisol release in the face of illness or stress is vital for survival. Relative adrenal insufficiency occurs when a patient's cortisol response is inadequate for the degree of illness or stress. Numerous studies have documented the existence of relative adrenal insufficiency in critically ill adults, and its association with increased morbidity and mortality. There is increasing evidence that relative adrenal insufficiency may be an etiology for hemodynamic instability and hypotension in the critically ill newborn, but compared with the adult population, there is still a paucity of data in this population. Randomized controlled trials are needed to evaluate the efficacy and safety of glucocorticoids for the treatment of cardiovascular insufficiency due to relative adrenal insufficiency in ill preterm and term newborn infants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.