ReviewJournal of perinatology : official journal of the California Perinatal Association2009
Probiotic and prebiotic supplementation for the prevention of neonatal necrotizing enterocolitis.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 56 citations in OpenAlex.
- Effect of a Multi-Strain Probiotic on the Incidence and Severity of Necrotizing Enterocolitis and Feeding Intolerances in Preterm Neonates.Nutrients · 2022Trial
- The role of intestinal epithelial barrier function in the development of NEC.Tissue barriers · 2015Article
- Article
- Microbiota diversity and stability of the preterm neonatal ileum and colon of two infants.MicrobiologyOpen · 2013Article
- The altered gut microbiome and necrotizing enterocolitis.Clinics in perinatology · 2013Review
- Fulminant necrotizing enterocolitis in a multihospital healthcare system.Journal of perinatology : official journal of the California Perinatal Association · 2012Article
- The human microbiome and surgical disease.Annals of surgery · 2011Article
- The intestinal microbiome of infants and the use of probiotics.Current opinion in pediatrics · 2011Review
- Beyond bacteria: a study of the enteric microbial consortium in extremely low birth weight infants.PloS one · 2011Article
- New concepts of microbial translocation in the neonatal intestine: mechanisms and prevention.Clinics in perinatology · 2010Review
- Novel perspectives in probiotic treatment: the efficacy and unveiled mechanisms of the physiological functions.Clinical journal of gastroenterology · 2010Article
- Role of the gut microbiota in defining human health.Expert review of anti-infective therapy · 2010Review
- Probiotics: progress toward novel therapies for intestinal diseases.Current opinion in gastroenterology · 2010Review
- Microecology, intestinal epithelial barrier and necrotizing enterocolitis.Pediatric surgery international · 2010Review
- Review
- Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathophysiology of necrotizing enterocolitis (NEC) has not been clearly elucidated, but recent studies support the role of unbalanced pro-inflammatory signaling, leading to intestinal necrosis in premature infants. Although breast milk feeding is thought to reduce the risk of this condition, there are no preventive or therapeutic approaches that have consistently shown to be effective for this common and devastating disease. Recent studies show that probiotic colonization is abnormal in preterm neonates, and enteral supplementation with a variety of probiotic organisms can reduce the risk of disease. This chapter summarizes the current state-of-the-art regarding probiotics and NEC, but suggests caution until appropriately regulated products are available for use in this high-risk population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.