Evidence map›Paper›PMID 19398132›Full record

ArticleTrends in neurosciences2009

Common astrocytic programs during brain development, injury and cancer.

Daniel J Silver, Dennis A Steindler

Open access · greenAbstract read
In one paragraph

Article in Trends in neurosciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 50 citations in OpenAlex.

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  17. Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel J SilverThe Evelyn F. and William L. McKnight Brain Institute, The University of Florida, 100 South Newell Drive, P.O. Box 100015, Gainesville, FL 32610-0015, USA.
Dennis A Steindler
University of Florida · US

Funding

STEM/PROGENITOR CELL PROTECTION FOR PARKINSON'S DISEASER01NS055165 · NINDS · UNIVERSITY OF FLORIDA · PI STEINDLER, DENNIS A. · 2007 to 2011
$1.6M
NINDS NIH HHS R01 NS055165
6 · The paper itself

Abstract

In addition to radial glial cells of neurohistogenesis, immature astrocytes with stem-cell-like properties cordon off emerging functional patterns in the developing brain. Astrocytes also can be stem cells during adult neurogenesis, and a proposed potency of injury-associated reactive astrocytes has recently been substantiated. Astrocytic cells might additionally be involved in cancer stem cell-associated gliomagenesis. Thus, there are distinguishing roles for stem-cell-like astrocytes during brain development, in neurogenic niches in the adult, during attempted reactive neurogenesis after brain injury or disease and during brain tumorigenesis.

Indexed as

AdultAnimalsAnimals, NewbornAstrocytesBrainBrain DiseasesBrain InjuriesBrain NeoplasmsCell DifferentiationExtracellular MatrixHumansModels, BiologicalNeoplastic Stem CellsNeurogenesisStem Cells

Identifiers

PMID19398132
PMCPMC3033226
OpenAlexW2060260375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.