ArticleGene2009
DNA methylation analysis of the mammalian PEG3 imprinted domain.
Article in Gene, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 55 citations in OpenAlex.
- Mammalian DNA methyltransferases in DNA methylation and imprinted gene expression in extraembryonic ectoderm of post-implantation embryos.The Journal of biological chemistry · 2026Article
- Candidate imprinting control regions in dog genome.BMC genomics · 2025Article
- Short Communication: The imprinted and paternally expressed MIMT1 lncRNA ortholog in pigs.Journal of animal science · 2025Article
- Inheritance of paternal lifestyles and exposures through sperm DNA methylation.Nature reviews. Urology · 2023Review
- Along the Bos taurus genome, uncover candidate imprinting control regions.BMC genomics · 2022Article
- Systems biology comprehensive analysis on breast cancer for identification of key gene modules and genes associated with TNM-based clinical stages.Scientific reports · 2020Article
- Regulating tumor suppressor genes: post-translational modifications.Signal transduction and targeted therapy · 2020Review
- Role of the zinc finger and SCAN domain-containing transcription factors in cancer.American journal of cancer research · 2019Review
- The role of PEG3 in the occurrence and prognosis of colon cancer.OncoTargets and therapy · 2019Article
- Allele and dosage specificity of the Peg3 imprinted domain.PloS one · 2018Article
- Strand-specific CpG hemimethylation, a novel epigenetic modification functional for genomic imprinting.Nucleic acids research · 2017Article
- Article
- PEG3 control on the mammalian MSL complex.PloS one · 2017Article
- Parental and sexual conflicts over the Peg3 imprinted domain.Scientific reports · 2016Article
- Sex and Tissue Specificity of Peg3 Promoters.PloS one · 2016Article
- Phylogenetic and Epigenetic Footprinting of the Putative Enhancers of the Peg3 Domain.PloS one · 2016Article
- Article
- PEG3 Interacts with KAP1 through KRAB-A.PloS one · 2016Article
- Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation.Genome research · 2015Article
- Breast cancer risk and imprinting methylation in blood.Clinical epigenetics · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In this study, we performed the first systematic survey of DNA methylation status of the CpG islands of the PEG3 (Paternally expressed gene 3) imprinted domain in the mouse, cow, and human genomes. Previous studies have shown that the region surrounding the first exon of PEG3 contains a differentially methylated CpG island. In addition, we have discovered two previously unreported differentially methylated regions (DMR): one in the promoter region of mouse Zim3 and another in the promoter region of human USP29. In the cow, the Peg3-CpG island was the only area that showed DMR status. We have also examined the methylation status of several CpG islands in this region using human tumor-derived DNA. The CpG islands near PEG3 and USP29 both showed hypermethylation in DNA derived from breast and ovarian tumors. Overall, this study shows that the PEG3 imprinted domain of humans, cows, and mice contains differing numbers of DMRs, but the PEG3-CpG island is the only DMR that is conserved among these three species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.