ArticleLearning & memory (Cold Spring Harbor, N.Y.)2009
Stimulation of the lateral geniculate, superior colliculus, or visual cortex is sufficient for eyeblink conditioning in rats.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Triggering action potentials of a single neuron by multiphoton excitation elicits visually guided behavior.Nature communications · 2026Article
- Amygdala central nucleus modulation of cerebellar learning with a visual conditioned stimulus.Neurobiology of learning and memory · 2018Article
- A cerebellar mechanism for learning prior distributions of time intervals.Nature communications · 2018Article
- Morphological Constraints on Cerebellar Granule Cell Combinatorial Diversity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Article
- Purkinje cell activity during classical conditioning with different conditional stimuli explains central tenet of Rescorla–Wagner model [corrected].Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Cerebellar learning mechanisms.Brain research · 2015Review
- Learning-related neuronal activity in the ventral lateral geniculate nucleus during associative cerebellar learning.Journal of neurophysiology · 2014Article
- Inactivation of the ventral lateral geniculate and nucleus of the optic tract impairs retention of visual eyeblink conditioning.Behavioral neuroscience · 2013Article
- Visual cortical contributions to associative cerebellar learning.Neurobiology of learning and memory · 2013Article
- Anatomical characterization of a rabbit cerebellar eyeblink premotor pathway using pseudorabies and identification of a local modulatory network in anterior interpositus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Classical eyeblink conditioning using electrical stimulation of caudal mPFC as conditioned stimulus is dependent on cerebellar interpositus nucleus in guinea pigs.Acta pharmacologica Sinica · 2012Article
- Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning.Learning & memory (Cold Spring Harbor, N.Y.) · 2011Review
- Ventral lateral geniculate input to the medial pons is necessary for visual eyeblink conditioning in rats.Learning & memory (Cold Spring Harbor, N.Y.) · 2010Article
- Article
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Authors and funding
3 authors.
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Abstract
The role of the cerebellum in eyeblink conditioning is well established. Less work has been done to identify the necessary conditioned stimulus (CS) pathways that project sensory information to the cerebellum. A possible visual CS pathway has been hypothesized that consists of parallel inputs to the pontine nuclei from the lateral geniculate nucleus (LGN), superior colliculus (SC), pretectal nuclei, and visual cortex (VCTX) as reported by Koutalidis and colleagues in an earlier paper. The following experiments examined whether electrical stimulation of neural structures in the putative visual CS pathway can serve as a sufficient CS for eyeblink conditioning in rats. Unilateral stimulation of the ventral LGN (Experiment 1), SC (Experiment 2), or VCTX (Experiment 3) was used as a CS paired with a periorbital shock unconditioned stimulus. Stimulation was delivered to the hemisphere contralateral to the conditioned eye. Rats in all experiments were given five 100-trial sessions of paired or unpaired eyeblink conditioning with the stimulation CS followed by three paired sessions with a light CS. Stimulation of each visual area when paired with the unconditioned stimulus supported acquisition of eyeblink conditioned responses (CRs) and substantial savings when switched to a light CS. The results provide evidence for a unilateral parallel visual CS pathway for eyeblink conditioning that includes the LGN, SC, and VCTX inputs to the pontine nuclei.
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