Evidence map›Paper›PMID 19395075›Full record

ArticleThe Journal of allergy and clinical immunology2009

Adolescents and asthma: why bother with our meds?

David R Naimi, Tovia G Freedman, Kenneth R Ginsburg, Daniel Bogen, Cynthia S Rand, Andrea J Apter

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00115323 nacompletednot on this map

Individualized Interventions to Improve Asthma Adherence

TypeinterventionalSponsorUniversity of PennsylvaniaRan2005 to 2010Enrolled397ConditionsAsthma, Lung DiseasesArmsProblem Solving, Attention Control
NCT03842033 naactive not recruitingnot on this mapstarted 2019, after this paper: background citation

Implementing a Guidelines-Based M-Health Intervention for High Risk Asthma Patients

TypeinterventionalSponsorArkansas Children's Hospital Research InstituteRan2019 to 2027Enrolled370ConditionsPediatric AsthmaArmsPEAKmAAP, PEAKmAAP-DS, NutriMap Usual Care
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Pooled it
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  9. Perception of burden of oral and inhaled corticosteroid adverse effects on asthma-specific quality of life.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
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  19. Chronic stress and asthma in adolescents.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

David R NaimiDivision of Allergy and Immunology, the Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Tovia G Freedman
Kenneth R Ginsburg
Daniel Bogen
Cynthia S Rand
Andrea J Apter
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · USJohns Hopkins Medicine · US

Funding

Individualized Interventions to Improve Asthma AdherenceR01HL073932 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI APTER, ANDREA J. · 2005 to 2009
$3.6M
Literacy and improving patient-clinician encounters for AsthmaK02HL088469 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI APTER, ANDREA J. · 2007 to 2011
$526k
NHLBI NIH HHS HL070392NHLBI NIH HHS HL088469NHLBI NIH HHS K02 HL088469NHLBI NIH HHS R01 HL073932
6 · The paper itself

Abstract

backgroundAdherence to inhaled steroid regimens for asthma is poor in adults and children. Although it is assumed that nonadherence contributes to morbidity in older adolescents, investigation is limited.

objectiveWe sought to describe adherence to preventive asthma medications and explore relevant beliefs and attitudes in older urban adolescents, including their ideas for improving adherence.

methodsQuantitative and qualitative methods were used to collect data from a convenience sample of adolescents with asthma previously prescribed fluticasone/salmeterol (F/S). Two semistructured face-to-face interviews were conducted 1 month apart and analyzed for themes. F/S use was electronically monitored between visits and calculated as the number of actuations divided by the number of inhalations prescribed.

resultsForty participants, (15-18 years of age, 19 female subjects, 30 black/African American subjects, 11 Medicaid-insured subjects, and 24 previously hospitalized for asthma) with a median FEV1 of 98% of predicted value (range, 67% to 127%) had median adherence of 43% (range, 4% to 89%). Adherence was not associated with FEV1 or emergency department visits. Themes emerged from interviews as follows. Teens (1) take F/S inconsistently; (2) believe F/S is "supposed to help me breathe"; (3) dislike its taste; (4) are "too busy" and "forget"; and (5) recommend "reminder" solutions to poor adherence. Twenty percent believed that taking F/S was unnecessary, and another 18% expressed ambivalence about its benefits.

conclusionAdherence was poor. Examining and acknowledging health beliefs of older teens in the context of their complicated lives might facilitate discussions about self-management.

Indexed as

Medication AdherenceAdministration, InhalationAdolescentAlbuterolAndrostadienesAnti-Asthmatic AgentsAsthmaAttitude to HealthBronchodilator AgentsCohort StudiesFemaleFluticasoneHumansLogistic ModelsMaleSalmeterol XinafoateAlbuterolAndrostadienesAnti-Asthmatic AgentsBronchodilator AgentsFluticasoneSalmeterol Xinafoate

Identifiers

PMID19395075
PMCPMC3064885
OpenAlexW2084932017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.