Evidence map›Paper›PMID 19393959›Full record

SynthesisThe Lancet. Infectious diseases2009

Incubation periods of acute respiratory viral infections: a systematic review.

Justin Lessler, Nicholas G Reich, Ron Brookmeyer, Trish M Perl, Kenrad E Nelson, Derek A T Cummings

Abstract readSystematic Review
In one paragraph

Synthesis in The Lancet. Infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 448 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
448citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

448 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  11. Characterizing the impact of incorporating spatially aggregated human mobility data into infectious disease models.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Influenza.Nature reviews. Disease primers · 2026
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Informing quarantine policy for measles control in primary school and daycare settings: insights from a simulation study, Flanders, Belgium.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  19. Article
  20. Article

388 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Justin LesslerDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Nicholas G Reich
Ron Brookmeyer
Trish M Perl
Kenrad E Nelson
Derek A T Cummings

Funding

Computational Models of Infectious Disease ThreatsU01GM070708 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BURKE, DONALD SCOTT · 2004 to 2008
$3.8M
Ecology of Infectious Diseases (EID)-Immune Landscapes of Human Influenza in HousR01TW008246 · FIC · JOHNS HOPKINS UNIVERSITY · PI CUMMINGS, DEREK A · 2008 to 2011
$1.9M
FIC NIH HHS R01 TW008246NIGMS NIH HHS U01 GM070708NIGMS NIH HHS U01-GM070708PHITPO CDC HHS HK00014PHITPO CDC HHS U38 HK000014
6 · The paper itself

Abstract

Knowledge of the incubation period is essential in the investigation and control of infectious disease, but statements of incubation period are often poorly referenced, inconsistent, or based on limited data. In a systematic review of the literature on nine respiratory viral infections of public-health importance, we identified 436 articles with statements of incubation period and 38 with data for pooled analysis. We fitted a log-normal distribution to pooled data and found the median incubation period to be 5.6 days (95% CI 4.8-6.3) for adenovirus, 3.2 days (95% CI 2.8-3.7) for human coronavirus, 4.0 days (95% CI 3.6-4.4) for severe acute respiratory syndrome coronavirus, 1.4 days (95% CI 1.3-1.5) for influenza A, 0.6 days (95% CI 0.5-0.6) for influenza B, 12.5 days (95% CI 11.8-13.3) for measles, 2.6 days (95% CI 2.1-3.1) for parainfluenza, 4.4 days (95% CI 3.9-4.9) for respiratory syncytial virus, and 1.9 days (95% CI 1.4-2.4) for rhinovirus. When using the incubation period, it is important to consider its full distribution: the right tail for quarantine policy, the central regions for likely times and sources of infection, and the full distribution for models used in pandemic planning. Our estimates combine published data to give the detail necessary for these and other applications.

Indexed as

Infectious Disease Incubation PeriodAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansInfantMaleMiddle AgedRespiratory Tract InfectionsYoung Adult

Identifiers

PMID19393959
PMCPMC4327893

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.