ReviewJournal of physiology and biochemistry2008
Nutrient sensing in the gastrointestinal tract: possible role for nutrient transporters.
Review in Journal of physiology and biochemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- The role of diet in the pathophysiology and management of irritable bowel syndrome.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Review
- Possible role of intestinal stem cells in the pathophysiology of irritable bowel syndrome.World journal of gastroenterology · 2020Review
- Diet in Irritable Bowel Syndrome (IBS): Interaction with Gut Microbiota and Gut Hormones.Nutrients · 2019Review
- Effect of diet and individual dietary guidance on gastrointestinal endocrine cells in patients with irritable bowel syndrome (Review).International journal of molecular medicine · 2017Review
- Dietary fiber in irritable bowel syndrome (Review).International journal of molecular medicine · 2017Article
- Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease.World journal of gastroenterology · 2017Review
- Changes in duodenal enteroendocrine cells in patients with irritable bowel syndrome following dietary guidance.Experimental biology and medicine (Maywood, N.J.) · 2017Article
- Dietary guidance and ileal enteroendocrine cells in patients with irritable bowel syndrome.Experimental and therapeutic medicine · 2016Article
- Interaction between diet and gastrointestinal endocrine cells.Biomedical reports · 2016Article
- Changes in small intestinal chromogranin A-immunoreactive cell densities in patients with irritable bowel syndrome after receiving dietary guidance.International journal of molecular medicine · 2016Article
- Dietary guidance normalizes large intestinal endocrine cell densities in patients with irritable bowel syndrome.European journal of clinical nutrition · 2016Article
- Recent developments in the pathophysiology of irritable bowel syndrome.World journal of gastroenterology · 2015Review
- Article
- Increased chromogranin a cell density in the large intestine of patients with irritable bowel syndrome after receiving dietary guidance.Gastroenterology research and practice · 2015Article
- Increased gastric chromogranin A cell density following changes to diets of patients with irritable bowel syndrome.Molecular medicine reports · 2014Article
- Stomach antral endocrine cells in patients with irritable bowel syndrome.International journal of molecular medicine · 2014Article
- Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity.Molecular metabolism · 2014Article
- Interaction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (review).International journal of molecular medicine · 2014Review
- Endocrine cells in the oxyntic mucosa of the stomach in patients with irritable bowel syndrome.World journal of gastrointestinal endoscopy · 2014Article
- Is irritable bowel syndrome an organic disorder?World journal of gastroenterology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Although it is well established that the presence of nutrients in the gut lumen can bring about changes in GI function, the mechanisms and pathways by which these changes occur has not been fully elucidated. It has been known for many years that luminal nutrients stimulate the release of hormones and regulatory peptides from gut endocrine cells and that luminal nutrients activate intrinsic and extrinsic neural pathways innervating the gut. Activation of gut endocrine cells and neural pathways by nutrients in the gut lumen is key in coordination of postprandial GI function and also in the regulation of food intake. Recent evidence suggests that these pathways can be modified by long term changes in diet or by inflammatory processes in the gut wall. Thus it is important to determine the cellular and molecular mechanisms underlying these processes not only to increase our understanding of as part of basic physiology but also to understand changes in these pathways that occur in the presence of pathophysiology and disease. This review summarizes some of the latest data that we have obtained, together with information from the other laboratories, which have elucidated some of the mechanisms involved in nutrient detection in the gut wall. The focus is on monosaccharides and protein hydrolysates as there is some evidence for a role for nutrient transporters in detection of these nutrients.
Indexed as
Identifiers
19391461What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.