Evidence map›Paper›PMID 19390556›Full record

ArticleNature reviews. Clinical oncology2009

Cerebral primitive neuroectodermal tumor in an adult with a heterozygous MSH2 mutation.

Alexander F Jeans, Ian Frayling, Bharat Jasani, Lucy Side, Claire Blesing, Olaf Ansorge

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Nature reviews. Clinical oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Alexander F JeansDepartment of Neuropathology, John Radcliffe Hospital, Oxford, UK. alexander.jeans@orh.nhs.uk
Ian Frayling
Bharat Jasani
Lucy Side
Claire Blesing
Olaf Ansorge
Churchill Hospital · GBJohn Radcliffe Hospital · GBCardiff University · GBUniversity Hospital of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA 37-year-old woman presented with a supratentorial cerebral mass, which was diagnosed histologically as a primitive neuroectodermal tumor. She had been treated for rectal adenocarcinoma 7 years previously. A family history revealed a young-onset colorectal carcinoma in the patient's father. INVESTIGATIONS: Immunohistochemical analysis for DNA mismatch repair proteins, germline mutation analysis of MSH2. DIAGNOSIS: Lynch syndrome with a heterozygous germline mutation in MSH2. MANAGEMENT: Debulking of the cerebral tumor, craniospinal axis radiotherapy, and genetic counseling of family.

Indexed as

HeterozygoteMutationAdultColorectal Neoplasms, Hereditary NonpolyposisDNA Mismatch RepairDNA Mutational AnalysisFatal OutcomeFemaleGerm-Line MutationHumansImmunohistochemistryMutS Homolog 2 ProteinNeuroectodermal Tumors, PrimitivePedigreeRadiographySequence Analysis, DNAMutS Homolog 2 Protein

Identifiers

PMID19390556
OpenAlexW2140129007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.