SynthesisJournal of the American Medical Informatics Association : JAMIA
What evidence supports the use of computerized alerts and prompts to improve clinicians' prescribing behavior?
Synthesis in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
123 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- The Effect of Computerized Alerts on Prescribing and Patient Outcomes: A Systematic Review.Applied clinical informatics · 2025Pooled it
- Pooled it
- Interventions to reduce the incidence of medical error and its financial burden in health care systems: A systematic review of systematic reviews.Frontiers in medicine · 2022Pooled it
- Manually-generated reminders delivered on paper: effects on professional practice and patient outcomes.The Cochrane database of systematic reviews · 2019Pooled it
- Clinical Decision Support Systems for Drug Allergy Checking: Systematic Review.Journal of medical Internet research · 2018Pooled it
- Computer-generated reminders delivered on paper to healthcare professionals: effects on professional practice and healthcare outcomes.The Cochrane database of systematic reviews · 2017Pooled it
- Effects of health information technology on patient outcomes: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2016Pooled it
- Usability Flaws in Medication Alerting Systems: Impact on Usage and Work System.Yearbook of medical informatics · 2015Pooled it
- The effectiveness of computerized order entry at reducing preventable adverse drug events and medication errors in hospital settings: a systematic review and meta-analysis.Systematic reviews · 2014Pooled it
- Interventions to improve safe and effective medicines use by consumers: an overview of systematic reviews.The Cochrane database of systematic reviews · 2014Pooled it
- The evidence for the effectiveness of safety alerts in electronic patient medication record systems at the point of pharmacy order entry: a systematic review.BMC medical informatics and decision making · 2013Pooled it
- Effects of clinical decision-support systems on practitioner performance and patient outcomes: a synthesis of high-quality systematic review findings.Journal of the American Medical Informatics Association : JAMIA · 2011Pooled it
- The impact of eHealth on the quality and safety of health care: a systematic overview.PLoS medicine · 2011Pooled it
- Impact of Agency Receipt of Incentives and Reminders on Engagement and Continuity of Care for Clients With Co-Occurring Disorders.Psychiatric services (Washington, D.C.) · 2018Trial
- Identifying Which Urban Children With Asthma Benefit Most From Clinician Prompting: Subgroup Analyses From the Prompting Asthma Intervention in Rochester-Uniting Parents and Providers (PAIR-UP) Trial.Academic pediatrics · 2018Trial
- Effect of a clinical decision support system on early action on immunological treatment failure in patients with HIV in Kenya: a cluster randomised controlled trial.The lancet. HIV · 2016Trial
- Public health communications and alert fatigue.BMC health services research · 2013Trial
- Clinical decision support to promote safe prescribing to women of reproductive age: a cluster-randomized trial.Journal of general internal medicine · 2012Trial
- A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis.Lancet (London, England) · 2012Trial
- A mnemonic for pharmacy students to use in pharmacotherapy assessment.American journal of pharmaceutical education · 2012Trial
63 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alerts and prompts represent promising types of decision support in electronic prescribing to tackle inadequacies in prescribing. A systematic review was conducted to evaluate the efficacy of computerized drug alerts and prompts searching EMBASE, CINHAL, MEDLINE, and PsychINFO up to May 2007. Studies assessing the impact of electronic alerts and prompts on clinicians' prescribing behavior were selected and categorized by decision support type. Most alerts and prompts (23 out of 27) demonstrated benefit in improving prescribing behavior and/or reducing error rates. The impact appeared to vary based on the type of decision support. Some of these alerts (n = 5) reported a positive impact on clinical and health service management outcomes. For many categories of reminders, the number of studies was very small and few data were available from the outpatient setting. None of the studies evaluated features that might make alerts and prompts more effective. Details of an updated search run in Jan 2009 are included in the supplement section of this review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.