Evidence map›Paper›PMID 19390051›Full record

ArticleScience (New York, N.Y.)2009

Revealing the history of sheep domestication using retrovirus integrations.

Bernardo Chessa, Filipe Pereira, Frederick Arnaud, Antonio Amorim, Félix Goyache, Ingrid Mainland, Rowland R Kao, Josephine M Pemberton, Dario Beraldi, Michael J Stear and 23 more

Abstract readHistorical Article
In one paragraph

Article in Science (New York, N.Y.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed.

  1. Adaptive landscape and genetic divergence of Karnah sheep revealed by selection scans across multiple ovine breeds.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors.

Bernardo ChessaInstitute of Comparative Medicine, Faculty of Veterinary Medicine, University of Glasgow, Glasgow G61 1QH, UK.
Filipe Pereira
Frederick Arnaud
Antonio Amorim
Félix Goyache
Ingrid Mainland
Rowland R Kao
Josephine M Pemberton
Dario Beraldi
Michael J Stear
Alberto Alberti
Marco Pittau
Leopoldo Iannuzzi
Mohammad H Banabazi
Rudovick R Kazwala
Ya-Ping Zhang
Juan J Arranz
Bahy A Ali
Zhiliang Wang
Metehan Uzun
Michel M Dione
Ingrid Olsaker
Lars-Erik Holm
Urmas Saarma
Sohail Ahmad
Nurbiy Marzanov
Emma Eythorsdottir
Martin J Holland
Paolo Ajmone-Marsan
Michael W Bruford
Juha Kantanen
Thomas E Spencer
Massimo Palmarini

Funding

Endogenous Retroviruses and Placental MorphogenesisR01HD052745 · NICHD · WASHINGTON STATE UNIVERSITY · PI SPENCER, THOMAS E · 2007 to 2011
$1.2M
Biotechnology and Biological Sciences Research Council BB/F014643/1NICHD NIH HHS HD05274NICHD NIH HHS R01 HD052745Wellcome Trust 076522Wellcome Trust 081696
6 · The paper itself

Abstract

The domestication of livestock represented a crucial step in human history. By using endogenous retroviruses as genetic markers, we found that sheep differentiated on the basis of their "retrotype" and morphological traits dispersed across Eurasia and Africa via separate migratory episodes. Relicts of the first migrations include the Mouflon, as well as breeds previously recognized as "primitive" on the basis of their morphology, such as the Orkney, Soay, and the Nordic short-tailed sheep now confined to the periphery of northwest Europe. A later migratory episode, involving sheep with improved production traits, shaped the great majority of present-day breeds. The ability to differentiate genetically primitive sheep from more modern breeds provides valuable insights into the history of sheep domestication.

Indexed as

SheepSheep, DomesticAnimal HusbandryAnimalsDNAEndogenous RetrovirusesGenetic MarkersHistory, AncientMolecular Sequence DataPolymorphism, GeneticPopulation DynamicsRetroviridaeVirus IntegrationDNAGenetic Markers

Identifiers

PMID19390051
PMCPMC3145132

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.