ArticleScience (New York, N.Y.)2009
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds.
Article in Science (New York, N.Y.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 408 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
408 citing papers in PubMed, 1 synthesis or guideline pooled it, 902 citations in OpenAlex.
- Genome-wide Association Studies for Female Fertility Traits in Chinese and Nordic Holsteins.Scientific reports · 2017Pooled it
- Multiple drivers of genomic novelty across ruminants.iScience · 2026Article
- Transition from Conventional to Genomic Selection (ssGBLUP) led to improve in accuracy gains and selection decisions in Sahiwal Cattle.Scientific reports · 2026Article
- Resolving Cattle GWAS Loci: Current Progress, Persistent Challenges and Future Directions.Current issues in molecular biology · 2026Review
- A portable recalibration workflow for reference-based variant calling in non-human genomes.PLoS computational biology · 2026Article
- Whole-Genome Resequencing Reveals Deep Genomic Differentiation and Highly Differentiated Segments Between a Composite Domestic Cattle Population and Yak from the Ili River Valley and Other Xinjiang Regions.Animals : an open access journal from MDPI · 2026Article
- Pangenome variation analysis uncovers the impacts of SNP-independent structural variations in modern European cattle breeding.iMetaOmics · 2026Article
- Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle.Evolutionary applications · 2026Article
- A comparative study on recombination activity in cattle.Genetics, selection, evolution : GSE · 2026Article
- Exploring Genomic Variability in the Mediterranean Buffalo Breed: A Step Towards Custom SNP Array.Animals : an open access journal from MDPI · 2026Article
- A comprehensive genomic characterization of Nellore cattle.BMC genomics · 2026Article
- Genomic Insights into the Origins, Population Structure, and Local Adaptation of Philippine Visayan Native Cattle.Animals : an open access journal from MDPI · 2026Article
- Population structure and domestication history of the Javan banteng.Current biology : CB · 2026Article
- Whole-genome sequencing reveals genomic diversity and selection signatures for adaptation in South African Afrikaner and Bonsmara cattle.Frontiers in genetics · 2026Article
- Exploring cattle structural variation in the era of long reads, pangenome graphs, and near-complete assemblies.Journal of animal science and biotechnology · 2025Review
- Selective sweeps for mutations increasing height impede identification of causative mutations for fertility and other correlated traits in cattle.Genetics, selection, evolution : GSE · 2025Article
- Overcoming limitations to customize DeepVariant for domesticated animals with TrioTrain.Genome research · 2025Article
- Article
- Population structure limits the use of genomic data for predicting phenotypes and managing genetic resources in forest trees.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Admixture and selection offer insights for the conservation and breeding of Guyuan cattle.BMC biology · 2025Article
348 more citing papers are in PubMed but not listed here.
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Authors and funding
92 authors.
Funding
Abstract
The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.