Evidence map›Paper›PMID 19389726›Full record

ArticleNucleic acids research2009

ANNIE: integrated de novo protein sequence annotation.

Hong Sain Ooi, Chia Yee Kwo, Michael Wildpaner, Fernanda L Sirota, Birgit Eisenhaber, Sebastian Maurer-Stroh, Wing Cheong Wong, Alexander Schleiffer, Frank Eisenhaber, Georg Schneider

Abstract read
In one paragraph

Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  20. Mutations in ROGDI Cause Kohlschütter-Tönz Syndrome.American journal of human genetics · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hong Sain OoiBioinformatics Institute, A*Star, Singapore.
Chia Yee Kwo
Michael Wildpaner
Fernanda L Sirota
Birgit Eisenhaber
Sebastian Maurer-Stroh
Wing Cheong Wong
Alexander Schleiffer
Frank Eisenhaber
Georg Schneider

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Function prediction of proteins with computational sequence analysis requires the use of dozens of prediction tools with a bewildering range of input and output formats. Each of these tools focuses on a narrow aspect and researchers are having difficulty obtaining an integrated picture. ANNIE is the result of years of close interaction between computational biologists and computer scientists and automates an essential part of this sequence analytic process. It brings together over 20 function prediction algorithms that have proven sufficiently reliable and indispensable in daily sequence analytic work and are meant to give scientists a quick overview of possible functional assignments of sequence segments in the query proteins. The results are displayed in an integrated manner using an innovative AJAX-based sequence viewer. ANNIE is available online at: http://annie.bii.a-star.edu.sg. This website is free and open to all users and there is no login requirement.

Indexed as

Sequence Analysis, ProteinSoftwareAlgorithmsUser-Computer Interface

Identifiers

PMID19389726
PMCPMC2703921

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.