Evidence map›Paper›PMID 19389485›Full record

ReviewThe international journal of biochemistry & cell biology2009

Structural and functional link between the mitochondrial network and the endoplasmic reticulum.

Carlotta Giorgi, Diego De Stefani, Angela Bononi, Rosario Rizzuto, Paolo Pinton

Abstract readReview
In one paragraph

Review in The international journal of biochemistry & cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 183 papers.

0numbers the graph read from it
0cells of the map it votes in
183citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

183 citing papers in PubMed.

  1. Review
  2. Review
  3. taVNS alleviates preeclampsia-induced vascular endothelial dysfunction via α7nAChR- IP3R1/GRP75/VDAC1 signal pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. The Noncanonical Wnt5a-CaJournal of cellular and molecular medicine · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Non-Vesicular Lipid Transport Machinery inInternational journal of molecular sciences · 2023
    Review
  19. Article
  20. Review

123 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlotta GiorgiDepartment of Experimental and Diagnostic Medicine, Section of General Pathology, Interdisciplinary Center for the Study of Inflammation (ICSI) and Emilia Romagna Laboratory BioPharmaNet, University of Ferrara, Via Borsari 46, 44100 Ferrara, Italy.
Diego De Stefani
Angela Bononi
Rosario Rizzuto
Paolo Pinton

Funding

TRANSLOCATION OF p66Shc: KINETICS, FUNCTION, APOPTOSISP01AG025532 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KIM, KYOUNGMI · 2007 to 2017
$12.1M
NIA NIH HHS 1P01AG025532-01A1NIA NIH HHS P01 AG025532Telethon GGP09128
6 · The paper itself

Abstract

Mitochondrial and endoplasmic reticulum (ER) networks are fundamental for the maintenance of cellular homeostasis and for determination of cell fate under stress conditions. Recent structural and functional studies revealed the interaction of these networks. These zones of close contact between ER and mitochondria called MAM (mitochondria associated membranes) support communication between the two organelles including bioenergetics and cell survival. The existence of macromolecular complexes in these contact sites has also been revealed. In this contribution, we will review: (i) the ER and mitochondria structure and their dynamics, (ii) the basic principles of ER mitochondrial Ca(2+) transport, (iii) the physiological/pathological role of this cross-talk.

Indexed as

AnimalsApoptosisCalcium SignalingEndoplasmic ReticulumHumansMitochondriaModels, Biological

Identifiers

PMID19389485
PMCPMC2731816

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.